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Pelvic Inflammatory Disease
Pelvic Inflammatory Disease
DISEASE
DEFINITION
Infection of the upper genital tract
Endometritis -infection of the uterine cavity
Salpingitis -infection of the tubes
Salpingo oophoritis -infection of tubes &
ovaries
Tubo-ovarian abscess
Pelvic peritonitis -infection of peritonium
epidemiology
Mainly affects women of child bearing
age
Commonly sexually acquired
Incidence 1-2% among sexually
active females
Organisms
Neisseria gonorrhoeae
Chlamydia trachomatis
commonest
E. coli, Group-B streptococcus &
staphylococcus
Anaerobic - Bacteroides
Mycoplasma hominis
Ureaplasma urealyticum
Mode of transmission
Ascending infection (Canalicular spread) COMMONEST
Ascend of gonococcal & chlamydial organisms by surface
extension from the lower genital tract through the cervical
canal by way of the endometrium to the fallopian tubes
Facilitated by the sexually transmitted vectors such as
sperms
Through uterine lymphatic & blood vessels across
parametrium
Gynecological procedures favouring ascend of infection
E.g. D&C, ERPC,IUI,Hysterosalpingography
Direct spread from contaminated structures in abdominal
cavity
E.g. Appendicitis
Risk factors
Diagnosis
Symptoms
Fever > 38 C
Abnormal vaginal discharge
Unexpected vaginal bleeding
Lower abdominal pain
Dyspareunia
Signs
Lower abdominal tenderness
PV adnexal tenderness
cervical excitation
Pyrexia
Differential diagnosis
Ectopic pregnancy
Acute appendicitis
Urinary tract infection
Endometriosis
Ovarian cyst accident
Investigations
FBC
CRP
High vaginal swabs
Ultra sound scan Tubo - ovarian
abscess
Laparoscopy gold standard to
diagnose, but perform only in
doubtful cases or if tubo-ovarian
abscess is suspected
Management
Start antibiotics empirically until confirmation by
investigations
Admit if systemically unwell
Analgesics
Antibiotics
Broad spectrum covering aerobes and anaerobes
Eg: Neisseria - cephalosporins,penicillins
Chlamydia - doxycycline,azythromycin
anaerobic - metranidazole
Complications
Tubo ovarian abcsess
Fitz Hugh Curtis syndrome
Peri hepatitis with PID
Fever right hypochondrial pain & tenderness
Chronic PID
Long term complication
Severe dysmenorrhoea
Recurrent episodes