MEDICATION SHEET

Name & Admin

(Generic &
Brand name;
Dosage, route,
frequency)
pantoprazole
sodium
Protonix
40 mg IV push
daily.

Mechanism of Action (Classification,

physiologic actions)

Side Effects

Nursing Responsibilites &

Patient Teaching

Rationale for use

with this patient

Proton pump inhibitor. Inhibits proton pump

activity by binding to hydrogen-potassium
adenosine triphosphatase, located at
secretory surface of gastric parietal cells, to
suppress gastric acid secretion

CNS: anxiety,
asthenia, dizziness,
headache,
insomnia,
migraine, pain.
CV: chest pain.
EENT: pharyngitis,
rhinitis, sinusitis.
GI: abdominal pain,
constipation,
diarrhea,
dyspepsia,
eructation,
flatulence,
gastroenteritis, GI
disorder, nausea,
rectal disorder,
vomiting.
GU: urinary
frequency, UTI.
Metabolic:
hyperglycemia,
hyperlipidemia.
Musculoskeletal:
arthralgia, back
pain, hypertonia,
neck pain.
Respiratory:
bronchitis,
dyspnea, increased
cough, upper
respiratory tract
infection.
Skin: rash.
Other: flulike
syndrome,
infection, injectionsite reaction.

Symptomatic response to
therapy doesnt preclude the
presence of gastric malignancy.
Alert: Prolonged use of proton
pump inhibitors may cause low
magnesium levels. Monitor
magnesium levels before start of
treatment and periodically
thereafter.
Alert: Monitor patient for signs
and symptoms of low
magnesium level, such as
abnormal heart rate or rhythm,
palpitations, muscle spasms,
tremor, or seizures. In children,
abnormal heart rate may present
as fatigue, upset stomach,
dizziness, and light-headedness.
Magnesium supplementation or
drug discontinuation may be
required.
Alert: May increase risk for
Clostridium difficileassociated
diarrhea (CDAD). Evaluate for
CDAD in patients who develop
diarrhea that doesnt improve.
Dont confuse Protonix with
Prilosec, Prozac, or Prevacid.
Dont confuse pantoprazole with
aripiprazole.
Instruct patient to take exactly
as prescribed and at about the
same time every day.Tell patient
to swallow tablet whole and not
to crush, split, or chew it. Tell
patient that antacids dont affect
drug absorption.
Teach patient to recognize and

Lower the acid level

in the stomach.
Treatment and
maintenance
therapy for ulcers.

report signs and symptoms of

low magnesium levels.