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DermatologaCMQ2010;8(2):110-116

Tularemia. Una revisin


Tularemia. A review.
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RESUMEN

ABSTRACT

La tularemia es una enfermedad infecciosa clsicamente trasmitida por vector, de reas geogrficas circunscritas, provocada
por Francisella tularensis, bacteria muy virulenta que provoca en el
ser humano diversos sndromes clnicos definidos. La enfermedad tiene especial relevancia debido a su potencial como arma
terrorista. El pronstico est determinado por la variedad clnica
y es curable con antibiticos.
P ALABRAS CLAVE : tularemia, Francisella tularensis

Tularemia is a vector transmited infectious disease caused by


Francisella tularensis, existent in well-known geographical areas.
The bacteria is highly virulent and promotes in humans a variety
of defined clinical syndromes. The disease has special relevance
because its potential role as terrorist weapon. Prognosis depends on clinical variety and is curable by antimicrobians.
K EYWORDS : tularemia, Francisella tularensis

Introduccin

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Sinnimos

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Historia

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CORRESPONDENCIA

DCMQ

110

Fotografa 1. Ciclo biolgico en la tularemia.

n rarenas98@hotmail.com, drfelac@yahoo.com
Departamento de Dermatologa del Hospital General Dr. Manuel Gea Gonzlez, SSA
Calzada de Tlalpan 4800, Mxico, D.F., 14080

Dermatologa cosmtica, mdica y quirrgica

Volumen 8 / Nmero 2 n abril-junio de 2010

TULAREMIA

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Por qu se llama tularemia?

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Historia de la tularemia en Mxico

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Volumen 8 / Nmero 2 n abril-junio de 2010

Francisella tularensis como arma biolgica

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Microbiologa
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Epidemiologa

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Dermatologa cosmtica, mdica y quirrgica

DCMQ

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ARTCULOS DE REVISIN

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Qu son las garrapatas?

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CPSOF EFTDSJCJFSPO FM QBQFM QBUPHnOJDP EF MB HBSSBQBUB 

DCMQ

112

Dermatologa cosmtica, mdica y quirrgica

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Mecanismo de contagio

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La tularemia como amenaza terrorista

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GFSNP  $wNPFTUBSFNPTFO.nYJDP

Volumen 8 / Nmero 2 n abril-junio de 2010

TULAREMIA

Patognesis

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4FIBEFTDSJUPVOBQSJNFSBGBTFCBDUFSnNJDB DPOBDUJWB
DJwOEFMDPNQMFNFOUPZEFMTJTUFNBSFUrDVMPFOEPUFMJBM 

Cuadro clnico

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GSFDVFOUFBMBNFOPTGSFDVFOUFVMDFSPHBOHMJPOBS 

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DBTPTIBZQSwESPNPTDPODFGBMFB FCSFZBUBRVFBMFTUBEP
HFOFSBM

Ulcero-ganglionar

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BMUPOJWFMEFTPTQFDIB
Fotografa 2. Lesin primaria de forma ulcero-ganglionar.

Manifestaciones reactivas

-BUVMBSFNJBQVFEFEBSMVHBSBEJWFSTBTNBOJGFTUBDJPOFT
SFBDUJWBT DPNPFSJUFNBOVEPTP FSVQDJwONPSCJMJGPSNFZ
FSJUFNBNVMUJGPSNF      

Pulmonar

Fotografa 3. Linfadenopata tularmica.

Volumen 8 / Nmero 2 n abril-junio de 2010

&TUB GPSNB DMrOJDB NFSFDF FTQFDJBM NFODJwO EFCJEP BM


SJFTHP QPS CJPUFSSPSJTNP &T VO DVBESP BMUBNFOUF MFUBM 
DPONPSUBMJEBEEFB QSPWPDBEBTPCSFUPEPQPS
MBTVCFTQFDJFUVMBSFOTJT4FDBSBDUFSJ[BQPSFCSFBMUB QPT
USBDJwO UPT EJTOFB EPMPSQFDUPSBM EJDVMUBESFTQJSBUPSJB
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ZWwNJUP BTrDPNPBMUFSBDJwOEFMFTUBEPEFBMFSUBZEJTP
DJBDJwO QVMTPUFNQFSBUVSB  DPNP FO FCSF UJGPJEFB 3B
EJPHSgDBNFOUFMPTEBUPTQVFEFOTFSNVZWBSJBEPTZTJ
NVMBSNVDIBTPUSBTFOGFSNFEBEFT EFTEFMJOGBEFOPQBUrB
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EFSSBNFQMFVSBM

Dermatologa cosmtica, mdica y quirrgica

DCMQ

113

ARTCULOS DE REVISIN

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lulas gigantes (HE 40x).
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DCMQ

114

Dermatologa cosmtica, mdica y quirrgica

Volumen 8 / Nmero 2 n abril-junio de 2010

TULAREMIA

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Pronstico

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Tratamiento

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HBSSBQBUB
BQMJDBSQFSNFUSJOBBMBSPQB SFWJTBSQFMP PSF
Volumen 8 / Nmero 2 n abril-junio de 2010

KBT BYJMBTZQJFSOBTTJTFFOUSBFOFMNFEJPEFMWFDUPS BTr


DPNPWFTUJSDBMDFUBTBKVTUBEBTZQBOUBMwOMBSHP
1BSBFMEFTBSSPMMPEFMBTWBDVOBTEFrOEPMFWFUFSJOBSJP
TFIBOSFBMJ[BEPFTUVEJPTFYQFSJNFOUBMFTDPOBOJNBMFT Z
FTDMBSPRVFBMHVOBTEFFTUBTWBDVOBTQVFEFOTFSWJSQBSB
QSPUFHFS FTQFDJFT EF JNQPSUBODJB QFDVBSJB  OP PCTUBOUF 
B|OOPFYJTUFMJDFODJBOJBQSPCBDJwOEFMB'%"QBSBUBM
VTP&OMBBDUVBMJEBE QBSBFWJUBSDPOUBHJPFOUSFBOJNBMFT
TFQSPIrCFMBDSrBEFBOJNBMFTFYwUJDPTZMBWFOUBMJCSFEF
BOJNBMFTTJMWFTUSFT 

Tularemia en embarazadas

&MDVBESPOPEJFSFEFMBTOPFNCBSB[BEBT4FSFDPNJFO
EB FWJUBS MB WBDVOBDJwO DPO CBDUFSJBT WJWBT BUFOVBEBT
&TUgOPCWJBNFOUFDPOUSBJOEJDBEBTMBTRVJOPMPOBTPUFUSB
DJDMJOBTQBSBUSBUBSFTUBJOGFDDJwO

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Volumen 8 / Nmero 2 n abril-junio de 2010

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