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spasmolytics
can be classified into three major subclasses:
1. Antimuscarinics (e.g., cimetropium, prifinium)
2. Smooth muscle relaxants (i.e., drugs that directly inhibit smooth muscle
contractility,
e.g., by increasing cyclic AMP levels or interfering with the intracellular
calcium
pool: tiropramide, papaverine-like agents (Singh et al., 2003), and
3. Ca+2-channel blockers (especially L-type Ca+2-channel blockers such as
nifedipine or
pinaverium and peppermint oil (Christen, 1990).