3D Printing of Tissue

Engineering Scaffolds

Akshay Pawar
(AM14M028)

Review Outline
Scaffolds in Tissue engineering
Traditional scaffolds
An Overview of 3D Printing
3D Printing processes
Examples

Scaffolds in Tissue engineering

Highly porous material act as a carrier for tissue regeneration
Provides physical supports and local environment
According to Hutmacher this scaffold must be
1.reabsorbable
2.biodegradable
3.3 dimensional, interconnected porous network
4.good surface chemistry
5.highly biocompatible

Traditional Scaffold generation

Solvent casting
fiber bonding
phase separation
gas induced foaming
salt leaching

Limitations

3D printing
developed by Massachusetts Institute of Technology, USA

http://www.hindawi.com/journals/ijp
s/2014/829145/fig1/

3D Printing processes
Different additive processes available for 3D printing
Selective laser sintering (SLS),
Stereolithography (SLA)
Fused deposition modeling (FDM)
Direct metal laser sintering (DMLS)
Digital light processing (DLP)
Electron beam melting (EBM)
Paper lamination technology (PLT)

Examples
Ear drum scaffold
Human nerves
3D printed bone
liver tissue engineering
cartilage
type 1 diabetes