CERTIFICATE OF ANALYSIS

Ritonavir Impurity F
Product Name
Chemical Name

Ritonavir Impurity F
Thiazol-5-ylmethyl (2S ,3S ,5S )-3-hydroxy-5-[(S )-4isopropyl-2,5-dioxoimidazolidin-1-yl]- 1,6diphenylhexan-2-ylcarbamate

Mol. Formula
Mol. Weight

C29H34N4O5S
550.67 g/mol

Batch No VSLS/RTN/IMP-F/15-16

Analysis Date

13-Nov-2015

Quantity 100mg

Retest Date

Nov-16

Packed

2X50mg

Storage

Preserve in Air tight container, protect from direct sunlight and for longer storage store at 2-8 C.

S.N.

Test

Result

Appearance

Off White solid

Solubility

Freely Soluble in Methanol

Identification by 1H NMR

Complies

Identification by Mass

Complies

Purity by HPLC

95.18%

Remarks: Based on 1H NMR, Mass and HPLC data, material confirms to the above product.

Prepared By

Approved by

Sign.
Date:

FRM/007-00

Quality Control Department