The influenza pandemic of 1918 killed an estimated 20 to 50 million people worldwide and infected over a quarter of the world's population. Known as the "Spanish Flu", it was exceptionally deadly because it caused a cytokine storm that triggered severe respiratory failure in otherwise healthy young adults unlike typical flu viruses which mainly threaten very young, old, or already weakened patients. No one is certain where it originated, but historians judge it was most likely caused by an H1N1 virus carrying genes from birds that had begun circulating in a less virulent form in 1915 and reemerged mutated in 1918.
The influenza pandemic of 1918 killed an estimated 20 to 50 million people worldwide and infected over a quarter of the world's population. Known as the "Spanish Flu", it was exceptionally deadly because it caused a cytokine storm that triggered severe respiratory failure in otherwise healthy young adults unlike typical flu viruses which mainly threaten very young, old, or already weakened patients. No one is certain where it originated, but historians judge it was most likely caused by an H1N1 virus carrying genes from birds that had begun circulating in a less virulent form in 1915 and reemerged mutated in 1918.
The influenza pandemic of 1918 killed an estimated 20 to 50 million people worldwide and infected over a quarter of the world's population. Known as the "Spanish Flu", it was exceptionally deadly because it caused a cytokine storm that triggered severe respiratory failure in otherwise healthy young adults unlike typical flu viruses which mainly threaten very young, old, or already weakened patients. No one is certain where it originated, but historians judge it was most likely caused by an H1N1 virus carrying genes from birds that had begun circulating in a less virulent form in 1915 and reemerged mutated in 1918.