With the presence of Glucose but no

lactose
*Repressor protein attaches to the
operator
* RNA polymerase blocked by repressor
NO TRANSCRIPTION

With the presence of both Glucose and

Lactose
*Repressor protein changes
configuration and does not attach to
operator
*RNA unstable and keeps falling from
promoter site
NO TRANSCRIPTION

With the presence of both Lactose and

no Glucose

With the absence of both Glucose and

Lactose

*Repressor protein changes

configuration and does not attach to
operator

*Repressor protein attaches to operator

*RNA polymerase attaches to promoter

site
HAVE TRANSCRIPTION

*RNA polymerase is blocked by repressor

NO TRANSCRIPTION