5/12/2016

Apreliminaryinvestigationofibogaine:casereportsandrecommendationsforfurtherstudy.PubMedNCBI

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Abstract
JSubstAbuseTreat.1994JulAug11(4):37985.

Apreliminaryinvestigationofibogaine:casereportsand
recommendationsforfurtherstudy.
SheppardSG.

Abstract
Anaturallyoccurringsubstance,ibogaine,wastakenbysevenindividuals
whowereaddictedtoopiates.Ibogaine,analkaloidwithpsychotropiceffects
atdosesof200300mgandabove,wastakeninsingledosesof7001800mg
bythesubjectsinthestudy.Attheendofthe2438hrpsychoactiveperiod
inducedbythedrugatthesedoses,noneofthesubjectsdisplayedsignificant
opiatewithdrawalsymptoms.Atthelowestdoseof700mg,onesubject
recontinuedhisdrugabuseafter2daysoftheremainingsixindividualswho
took1,000mgorabove,tworelapsedafteranumberofweeks,onereverted
tointermittentheroinuse,andthreeappeartohaveremaineddrugfree14
weeksormoreafterundergoingthisexperimentaltreatment.Ibogainemaybe
ofvalueinthepresentandcouldserveasamodelforthedevelopmentof
improvedagentsforthetreatmentofsubstanceabuseinthefuture.
PMID:7966509[PubMedindexedforMEDLINE]

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