EIS SYSTEM

technology
EIS Signal
Processin
g Analysis

EIS Description

EIS Performances

EIS Measurement

Software Features and

used Technologies

Bio Impedance
technologies in bipolar
mode
Signal Processing
analysis In 3 steps
Modeling

Bio Impedance
Technologies
Step
#

Sequence
Type

Pulse
Duration

Pulse
Count

1Hz.

30 ms

704

700 Hz

30 ms

704

3
4

1KHz
DC

30 ms
30 ms
.

704
704

Purposes
EPI : Na+/K+ATPase pump activity
BIA: tissue pCO2
BIP : micro circulation Blood flow
GSR : Sympathetic system activity

Signal Processing Analysis 1

Signal Processing Analysis 2

Signal Processing Analysis 3

RESULTS OF THE EIS

MEASUREMENT

Modeling

Verification and Validation of the

EIS Modeling

Results of the modeling

EIS Clinical Investigation Botkin

2006
Monitoring of the EIS system versus laboratory test
(TSH) with the thyroid substitute treatment r2 = 0.79
P< 0.0001
Monitoring of the EIS system versus NIBP
measurement with the Beta blockers treatment r2 =
0.78 P< 0.0001
Monitoring of the EIS system versus NIBP
measurement with CEI treatment r2 = 0.78 P<
0.0001
Monitoring of the EIS system versus laboratory test
(Pro thrombin Time) with the anticoagulant treatment
r2 = 0.91 P< 0.0001
Monitoring of the EIS system versus the depressions
symptomatology with the SSRI's treatment
r2 = 0.87 P< 0.0001

EIS Clinical Investigation

Caudal 2007
The volume 9/10 of the ESG graph of the group
diagnosed was 14.7 +/- 5 10-6 S.m-1 and the
non-ADHD children was 4.7 +/-2.7 10-6 S.m-1
(P<0.0001, and P<0.0001 respectively)
The volume 1/3/16/18 of the ESG graph of the
group diagnosed was3.1+/- 0.6 10-6 S.m-1
and the non-ADHD children was 4.7 +/- 0.7 106 S.m-1 (P<0.001, and P<0.001 respectively)
The volume 2/4/15/17 of the ESG graph of the
group diagnosed was 10.6 +/- 7 10-6 S.m-1
and the non-ADHD children was 28+/- 8 10-6
S.m-1 (P<0.0001, and P<0.0001 respectively)

REFERENCES
Peyman Mirtaheri, Sverre Grimnes, Orjan G
Martinsen and Tor Inge Tonnessen. A new
biomedical sensor for measuring PCO2.
Physiol. Meas. 25 (2004) 421436
Kun,S.,Ristic,B.,Peura,R.A.,and Dunn,R.M.,
"Algorithm for tissue ischemia estimation
based on electrical impedance
spectroscopy," IEEE Transactions on
Biomedical Engineering vol.50, no 12, pp.
1352-1359, 2003
Peyman Mirtaheri, Sverre Grimnes, and
Orjan G. Martinsen,. Electrode Polarization
Impedance in Weak NaCl Aqueous
Solutions. IEEE Transactions on Biomedical
Engineering vol. 52, no 12, December 2005

Thank you for your Time

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