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SCHIZOPHRENIA

By:
Simon, Kenneth Paul Blum, Julia and Ciara

What is Schizophrenia?
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Schizophrenia is a severe mental disorder, characterized by profound


disruptions in thinking, affecting language, perception, and the sense of self. It
often includes psychotic experiences, such as hearing voices or delusions.
Schizophrenia affects more than 21 million people worldwide.
It is a treatable disorder.
One in two people living with schizophrenia does not receive care for the
condition.

Solution & Structure


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Our solution is similar to an insulin pump because our product pumps drugs
straight into the body, but risperidone instead of insulin.
Our container holds 28 ml of concentrated risperidone. The solubility of
risperidone into ph7.2 water is 1 mg/2 ml so the container holds 7 days worth
of medicine.
Our pump would run on a timer which would periodically release 2 mg of
risperidone into the body
Our pump would have a long tube which connects to a plastic needle that
needs to be inserted into the body and changed once every week. The needle
needs to be changed to a different spot every week to avoid infection. The
needle must be placed at least one inch away from the last place

Previously Attempted Solutions


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conventional antipsychotics
- binds to dopamine receptors, but do not stimulate them, blocks them
- atypical antipsychotics
- aim: less side effects
- only blocks dopamine temporarily, then return to normal
- antidepressant medications
- electroconvulsive therapy
- seizure in patients reduced symptoms
- usually 3-15 treatments
- new drug is called paliperidone palmitate. It's an injectable form of the secondgeneration, or "atypical," antipsychotic medication Invega.
- one shot a month
- most common side effects were weight gain and stomach flu

Virtual Mentor
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We were unable to get a response from our virtual mentor therefore we cant
conclude the reasonability of our product.
Online sources such as RxList aka The Internet Drug Index has files of
multiple studies done in similar fashion that conclude it would be a viable
option.

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