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Pharmaceutical Calculations: Child Dose
Pharmaceutical Calculations: Child Dose
Pharmaceutical Calculations: Child Dose
TPN CALCULATIONS:
a. 153.84 cc a. 110 mg
b. 456.34 cc b. 41.52 mg
c. 212.5 cc c. 63.20 mg
d. 121.12 cc d. 71.42 mg
6. How many milligrams are equal to 1/ 11. If an adult dose of drug is 750mg, what
200 grain of nitroglycerine ? is the dose for child weighing 20 lbs ?
a. 250 mg a. 25.53 mEq
b. 150 mg b. 15.67 mEq
c. 50 mg c. 38.46 mEq
d. 100 mg d. 45.20 mEq
12. If an adult dose of drug is 100mg, what 17. How many milliequivalents of ferrous
would be dose for a child that has a body are present in 5 gr of ferrous sulfate? [ MW =
surface area 0.9 m2 ? 152 gm/mole]
13. If therapeutic dose of drug is 10mg/kg/ 18. What is the half-life of drug that has rate
day, how many 250mg/100cc ready-infusions- constant 0.067 days -1 ? [ First order kinetic]
bags should be filled ? Patient’s weight is 156
lbs. a. 12.11 days
b. 5.56 days
a. 3 bags c. 10.34 days
b. 1 bags d. 3.25 days
c. 2 bags
d. 8 bags 19. What is a rate of constant of the drug
having initial concentration of drug 1000mg/cc
14. How many cc of water should mix with and 100mg/cc after 90 minutes ?
70% alcohol to prepare 750cc of 20% alcohol?
a. 0.025 min-1
a. 625.10 cc b. 0.5 min-1
b. 714.5 cc c. 2.2 min -1
c. 332.89 cc d. 3.2 min-1
d. 531.71 cc
20. What is a rate of constant of heparin in
15. Aluminum (Al +3) has a gram atomic first order kinetic if 50 units/cc of heparin
weight of 27. What would be the milliequivalent remains in solution after 10 days ? [ Initial
weight ? concentration of heparin was 5000 units/cc]
a. 81 a. 2.1 day-1
b. 9 b. 0.5 day-1
c. 3 c. 0.46 day-1
d. 27 d. 1.23 day-1
16. How many mEq of Na+ presents in 21. What is an apparent volume of distribu-
0.9% 250cc of normal saline solution ? tion of 0.25mg lanoxin with plasma concentra-
(MW = 58.5 gram/mole) tion of 0.1 ng/cc ?
a. 2.5 ml 26. What would be total calories provided
b. 2.5 x 109 ml by TPN mixture containing 1200cc D5W,
c. 0.025 ml 1000cc of 10% aminoacids, 100cc of 5%
d. 2.5 x 10 15 ml alcohol and 300cc of 20% fat emulsion ?
5 (a) To solve this kind of problem we have 9 (b) pH = PKa + log salt
acid
to use alligation method.
7 = 5 + log salt
acid
75 20 (75%)
2 = log salt/acid
30
(salt/acid) = 10-2
14 (d) To solve this kinds of problem, Amount of NaCl in 0.9 % 250cc of normal
we have to use alligation method. saline solution is = 250 x 0.009 = 2.25 gm,
therefore we can say 2.25 units NaCl is disso-
70 20 (70%) ciate in 2.25 units Na+ and 2.25 units Cl- ions.
22 (a) Patient is weighing 150 lbs = 68.18 kg 100cc of 5% alcohol solution contains
2.2 = 100 x 0.05 x 5.6 calories = 28 calories
A normal therapeutic dose in an adult patient is
= 68.18 x 20 1cc of 20% fat emulsion provides = 2 calories
= 1363 mcg per twice a week. 300cc of 20% lipid solution will provide
= 681.81 mcg per a week. = 300 x 2 = 600 calories
= 0.68 mg per a week.
Total calories provide = 204+400+28+600
23 (c) An I.V. admixture contains 1000mg of = 1232 calories.
drug in 250cc of solution, therefore one can say
27 (a) 50cc of 50% sodium bicarbonate
= 1000 mg = 4 mg/cc solution contains = 25 gm of sod bicarbonate.
250 cc
eq weight = gm mole wt
I.V. set delivers 20 drops per cc, therefore to valence
administer 50 mg dose of drug we require = 84 gm / 1 = 84 g
= 50 x 20 = 250 drops per minute.
4
mEq = eq wt
1000
= 84 / 1000 = 0.084 g
= 297.61 mEq
= 10 5 minutes.
1 cc contains 20 drops
0.69 cc will need ?
= 20 x 0.69cc
= 13.8 drops/min = 14 drops/min
= 250mg/ 6
= 41.66mg every 4-hour.