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Comparison between

HUMAN SKIN
and
PIG SKIN
 is a soft outer covering of an animal, in particular
a vertebrate. Other animal coverings such the
arthropod exoskeleton or the seashell have
different developmental origin, structure and
chemical composition. The adjective cutaneous
literally means "of the skin" (from Latin cutis,
skin). In mammal, the skin is the largest organ of
the integumentary skin made up of multiple
layers of ectodermal tissue, and guards the
underlying muscles, bones, ligaments and internal
organs.
We compared the penetration properties of
human, pig and rat skin with the
Graftskin™ LSE™ (living skin equivalent)
and the Skinethic™ HRE (human
reconstructed epidermis) models using
four topical dermatological drugs
(salicylic acid, hydrocortisone,
clotrimazole and terbinafine) with widely
varying polarity. In agreement with
published data, pig skin appeared as the
most suitable model for human skin: the
fluxes through the skin and
concentrations in the skin were of the
same order of magnitude for both tissues,
with differences of at most two- or
Fats
The hypodermis, also called the hypoderm,
subcutaneous tissue, or superficial fascia is
the lowermost layer of the integumentary
system in vertebrates. Types of cells that are
found in the hypodermis are fibroblasts,
adipose cells, and macrophages. It is derived
from the mesoderm, but unlike the dermis, it is
not derived from the dermatome region of the
mesoderm. In arthropods, the hypodermis is an
epidermal layer of cells that secretes the
chitinous cuticle. The term also refers to a layer
of cells lying immediately below the epidermis
of plants.
Diseases from
Fats
Obesity is a medical condition in which
excess body fat has accumulated to the extent
that it may have an adverse effect on health,
leading to reduced life expectancy and/or
increased health problems.

Hypertension or high blood


pressure is a chronic medical condition in
which the blood pressure in the arteries is
elevated. It is the opposite of hypotension. It
is classified as either primary (essential) or
secondary. About 90-95% of cases are termed
"primary hypertension", which refers to high
blood pressure for which no medical cause

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