2010

Xl

XL = LI.~E SCIENCES

Du rat ion : Three Hours

Maximum Marks; J (K)

Head the roUowing ~nstmcti.om carefuUy.

I . This quest ion paper contai ns 24 pages inc I udl ng bllll1 k p.&i!!'Cs for rough work, Please check all ~s and report discrepancy. i(any.

2. WrilC your r~_gistraJ..ion number, your namt and name of tbe exammanon cemre at Ihe specified locallons on the right half of !he Oplitil Response Sheet (ORS)-

:\. U sing HB pencil. darken the appropri alot~ bubble under each digit of yuur registration number and the letters correspondmg 10 your paper code.

4_ Alilhe questions in !his question paper Be of objecli~'e t)'pe.

S. Questions must be answered on Optical Re~ponse ShcC'! fORS) by darkening Ihe appropria1e bubble (marked A. B, C. D) usi ng H B pencil against lhc question number on the left hand side of the ORS. FOF each qoerrtloD: darken the bubble 01 tile eerreet .lI8Wer. III case you wish to dt4l1ge an answer, erase Ihe old answer eompletely. Mort Ihan one answer bubbled against a Question wiJl be taken as an j neorrect response.

6. There are :II lo<.a.I of 65 ll~sti005 canyio,g 100 rnar1cs..

7_ Thi~ question paper contains six sections as listed below. SectIODi' GA (Gem Aptitude) and U ((bt:misID') w; (;2rnpulMlQ' sC$:ti.Q,,~- Choose two mote ~cctions from the remaining secuons I through L.

SectIon p.No. S«tiGo hz.eNo.
GA- Genera! Aptitudl!' 02 1. Botany it)
H. CMmi.u/); 04 K. Mioobio!otY 15
L Biochemistry 07 L. Zoology 18 Using UB pencil, mark !.he sections you have chosen by d.:J.r~el1illg the appropriat~ bubbles 00 1M len hllnd side of the OIlS pm".ided. Makr SI.IR" you haR cmndIy bu.bIJIfd Ow sections you ban cbosm.. OIlS 'oIII"W tKJIl be n1lloated it UUs infOol'lQatlou is NOT ..n.td.

11_ There lire 10 questions cllrrying ]5 marks in General Aptitude {GA) section, which is oompul~- Questions Q_] • Q.:'i will carry J-mark each, and questions Q.6 - Q. 10 will carry 2-mark:s each.

9. Then: an: ISlluestions canying 2.5 matk~ in Chrmis,try sccuon paper (Section H), which is <Xllnpulsay. Questions Q.l - Q.5 .... iIl carty l-ma1k each. and questiom Q.6 - Q-15 will '"arT)' ::!.marks t.h ~lainin,g 1 ~r of oommon d~la and ! parr ()f linked questions. Quesnoes Q.12 and Q. 13 (I pair) art! common data questions ",,;th 2·marks each. ow! qut:slions Q.14 and Q- L'i (I pair) are linked answer questions with 2·marb each. The answer to the seconc question of the hnked answer questions depends on the answer to the rlrst question {If the pair. If lhe first question in the linked pair i_~ wrongly answered or is un ·a.ltempted. then the af1.1,.wer 10 lhe second question j n !he parr will not be e ... atuared,

10. Each of the other XL seeti Of! papers ~ Sections I through U contains 20 questions carry; ng :m nml:!:_ Qut5ti01l5 Q.l - Q. 10 .... ill carry I· mark. each and questions Q.I ! - Q.20 will C:uTY 2-m.lrks e3Ch.

II. Un-auempicd questions will carry zero marks.

l:;:. Wrnnt answers will c::my NI:[:GATJ VE marks, In GAo, for Q.1 - Q_5. y, mark ";11 be deducted. {Of each wrong answer MId for 0_6 - Q. I O. ~ mart will be deducted foc cadt "'TOng answer, hI XL Senion H. {or Q.I - Q.5. !1 mar1 will be deduacd for each ",TOng. answer an(! for Q_6 - O.l.l f. mart will be deducted for each \Io'fl;Ing answer, The quesnon pair (Q_14. Q. 15) is question~ wjth linked answers. There will be negative marks only for \IolOItg answer to the fir~t question of 1M ltnkt!d answer question pair. r!~r Q 14. ¥.mark will be deducted f~lr wrong answer. There is M negative mllrkillg. for Q.1S. In all other XL section papers (Section Il.hrcM.Jgh L). for Q.l - Q 10. ~ mark will he deducted for each wrong answer and f~~r Q. 11 - Q_20. +-;. mark ""'fiJi be deducted for each wron:g: answer

13 Calculator (",,·ilhCM.!t d<.il:l ({ml1ccti~ily) is allowed in rhe cx.tmmaLion hall. l4. Charts. gr~rh sheets or I ubl cs <lIT NOT all~'\1 .. cd in the cxuuun ~I i on hall.

l~. Rough work can be done on the question paper itself. AUl.huonaHy. blank pages are provided at the end M the question Ila~r for HX.lgh work.

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GA: General Aptitude (Compulsory) Q.l- Q.5 carry one mark each.

0·1 The question belo ..... consists oj a pair of related words [ollowed by four pairs of ..... -ords. Select lite parr that best expresses the relation in the original pair,

U nemployed : Wo"rke r

(A) fallow: land

(B) un a ware ; sleeper (C) wit: jester

(D) renovated: house

Q.2 Choo.~e the most appropriase word from the options given below to complete the faltowin~

sentence:

His rather casual remaoo on ponties - __ his lack or seriousness about 1M subjet:L

(A) masked

(B) belied

tel betrayed

(D) suppressed

Q,3 Which of the joll{Jwing options is the closest in meaning 10 the word below:

Circuitous

(A) cyclic (B) indirect

( C) confusing (0) crooked

QA 25 persons are in a room. 15 of them play hockey, 17 of them play football and 10 of them play both hockey and football, Then the number of persons playing neither hockey nor football )5:

{A) 2

(B) 17

(C) 13

(D) 3-

Q_5 Choose the most appmpriate word from the options given below to complete the following

sentence:

If we manage to ~_ our natural resources, we would leave 8 better planet for

our childn:n.

(A) uphold (B) restra i 11 (C) cherish {O} con serve

Q~6 - Q.I0 carry two marks each.

Q,6 5 ski lied workers can bui ld a wall in 20 days ~ 8 semi -sk i ned workers can bu ild . a wa II in 2S days ~ 10 unskilled workers can build a wall in 30 days. If a learn has 2 skilled. 6 semi-skilled and 5 unskilled workers, how long will it take to build the wall?

(A} 2J) days

(B) rs days

(C) ie days

{O) 15 days

Q,7 Given digits 2, 2. 3, 3, 3,4, 4. 4.4 how many distinct 4 digit numbers greater than 3000 can be formed?

(A) 5U

(B) 51

(C) 52

(O) 54

-----.---~-----~--------.------.-- . __ .. _---,.-----

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Q.g If 137 + 276 ;;;; 435 how much is 731 + 672?

(A) .'l:14

(B) 1403

{(:) l623

(D) ]5 n

Q.9 Hari (I-I). Gita (G). lrfan (I) • md Saira (S) <Ire siblings (i.e. brothers and sisters l. All were rom on ] !.I January. The age difference between any l\.H) successive siblings (lhal is born one after another) is less than J years. Gi ven the following facts:

L. Hari's age + Gila's age> lrfan' sage + Saira 's age.

1 L. The age difference between Gita and Saira is 1 year. However, Gila is not the oldest and Sa ira is not the youn gest,

Ill. There are no l wins.

J n what order were tbe y born {oldest first)?

(A) HS]G

(B)SOHI

(C) IGSH

(0) lHSG

Q.lO Modern warfare has changed from large scale dashes of armies to suppression of civilian popu la Uons. Chemical ... gents that do their work silenUy appear to be sui ted to such wa rfa re; and regretful1y, there exlst people in military tslabUshments who think that chemical agent.'iare usdulloob for their cause.

Which of tire !oJlow;n8 statements best sums up the meaning of Iht above passage. {A) Modern warfare hOI.'; resulted in civil strife.

(B) Chemical agents arc useful in modem warfare.

(C) Use of che rnical agents in warfare would be undcsirab leo

(D) People in military establishments like to usc chemical agents. in war.

END OF SECTION - GA

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H : CHEMISTRY (Compulsory) Q~l - Q.5 carry one mark each.

Q-L For a spontaneous process. the total entropy change (AS~ + I::..SIII~t:I) is

(A) equal to zero

(C) less than zero for endothermic process

(B) greater than zero

(D) less than zero for exothermic process

Q.2. A battery delivers a steady current of 1-25 A for 90 min utes, The total charge LQ' (in Coulomb units) is

(A) 6750

(8) 1Ol2-5

(C) 112.S

(D) 12.5

Q.3. Molecule that has no lone pair of electrons on the central atom (among the chokes) is

(A) XeF4

ro or,

(D) BF3

Q.4. The oxidatioa state of nickel atom in the coordination compound [Ni(NHlhCiJC1 is

(A)-l (B)O (C) +1 (D) +2
Q.5. The compound that is aromatic. among [be choices, is
0 (+) H
{A) (B) 0 (C) 0 (O) 0 Q.6 - Q.15 earry two marks each.

Q.6. Consider the following equilibrium reaction:

CO (g) + o, (g) ~ COO~ (g)

0.60 arm of CO and 1.10 arm of Ol were mixed in a constant volume reaction vessel al a particular temperature. After the equilibrium was established. 0-10 atm of COCb was observed. The eq_ uiU bri urn constant for the reaction is

(A) 0.02

(B) 0.15

(C) 0-2

(D) 6.6

Q.7. For a particular reaction. tbe use of a catalyst reduces the activation energy (E.) to one-third its ori gi nal ..... alue, The ratio of rate constants (kc.t..L~u.d I ~)'ZeIl) is

(A) 1 (B) 1/3 (C) e~p( 2Ea ) (D) exp(_S_)

3RT 3RT

Q.K Among heptan-Lol, heptan-2-ot heptan~3-o1 and beptan-s-ol. compounds those exhibit optical acti vity are

(A) heptan-z-ol and heptan-J-ol (C) heptan-3-o1 and heptan-d-ol

(B) beptan-2-o1 and heptan-4-o1 (0) heptan-f-ol and hepean-d-ol

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0.9-

Structure or the compound Y in the following reaction sequence is

O E3r~

AcOH

x

KOBu

y

Br'O

(A)

~

Or

(B) .........

(C)

o

(D) 0

Q.IO- The ionization energy follows the order (A) 0/ >02 >02->0/-

(C) O2-::> O~2- s o, + > O~

(B) O2 > O~4-)o O~l-> O2- (D) 0/-> 01 > 01- > 0/

Q-l L Reaction of Na2S03 with 2 equivalents of HCl produces a gas X, Solution of X in water is acidic in nature. X is

(B)Cb

Common Data Questions

Common Data ror Questiow: II aDd 13:

The ionization constants of phosphorous acid (HtPOj} are ~I :: 3 X 10-1 ~ ~ = L 7 X 10-1 Q.12. For a dilute solution of phosphorous add in a pH 5 buffer. tbe predominant species is

(A) H~PO~

(D) PO/-

Q-13- The structure of phosphorous acid is
R HO-P-OOH
(A) HO-P-OH (8) I
1 H
H
~ . .0 H OOH
HO-"6 \ '"
(C) (O) p
/~
H H 0 XL

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Linked Answer Questions

Cons ider the react i On sequence

MeO~

V

anhydrous AlCIJ

(major product)

x

j. 8'2' NaOH

-~-----y

Q.14_ The structure of X in the above reaction sequence is

MeO~

(A) U

MeO

~C) Oy

o

MeO'Q'°Y

(B) I

.0 a

Q.lS. The structure of Y in the above reaction sequence is

MoO,~~

(A) U OH

MeO

{C} ~

~OH

o

MeO'Q'Bf

(8) I

A

MeO

~O) 0

Br

END OF SECTION - H

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I : BIOCHEMISTRY

Q.l - Q~10 carry one mark each,

Q.l. Nucleolus is involved in the synthesis of

(A) rRNA

(B) lRNA

(C) DNA

(OJ mRNA

Q.2. In tryptophan operon, tryptophan acts as

(A) Repressor

(B) Ac(i vator

(C) Co-repressor

(D) Co-activator

Q.3. Positive selection of T cells ensures

(A) MHC restriction (C) TCR engagements

Q.4. A DNA-binding motif is

(A) Helix-loop-helix (B) Helix-tum-helix (C) Helical wheel

(B) Self tolerance

(0) Activation by co-sumulatory signal

(0) Loop-helix-loop

Q.5. Amino adds responsible for N~linked and Q-linked glycosylation of proteins are

(A) Asparagine and Aspartic acid (C) Glutamic add and Serine

(B) Ghuamine and Serine

(0) Asparagine and Threonine

Q.6. One of the following compounds IS NOT a neurotransmitter

(A) Dopamine

(B) Glutamic acid

(C) Histidine

(0) Glycine

Q.7. Approximate molecular weight (kDa) of the product after translation of a 390 bases mRNA will be

(A) 48

(B) 26

(C) 39

(D) 14

Q.8. Lineweaver-Burk plot is a plot of

1 I

(A) - v s r.::1

Vo lS J

(B) Vo vs [s]

(0) _1 vs Is]

Vo

Q.9. A mixture of proteins (W. X. Y. Z) elute from Sephadex 0·200 column in the order W. X. Y, Z_ The protein with maximum electrophoretic mobility on 5DS-PAGE win he

(A)W

(B) X

(C) y

(0) Z

Q.IO. Specific precursor for an prostaglandins is

(A) 01eic acid

(B) Arachidonic acid (C) Palmitic acid

Q~11 - Q.20 carry two marks each.

Q.l1, Chymotrypsin and lysozyme are involved respectively in

P, Removal of successi ve carboxy 1 terminal residues

Q. Hydrolytic cleavage of peptide bond

R. Cleavage of glycosidic C·O bond S- Oxygen transport in blood

(A) P, Q

(B) Q. R

(C) Q. S

(D) R, S

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Q-12. Match the items in Group 1 with those in Group 2

Group 1

P, lsotype switching Q- Clonal a nergy

R_ Class II MHC

S, &1 f lOl era nee

Group 2 t. v, domain

2. N on-responsi ve to sel f antigen

3. Non-responsive Tu cells

4. Pl" rnicrog I obu 1 in

(A) P-l, Q-4. R·), S-2 (C) r-r, Q·3. R-4. S-1

(B) P·2. Q-4. x-r. S·3 (0) P-2. Q-L R-3. S4

Q. J 3. Multiple RNA polymerase transcribes a DNA template, unwinding about 1.5 turns of DNA template per uanscription bubble. From the structural information of classical B-DNA, how many transcription bubbles are possible for a 180 base pair DNA molecule?

(A) 12

(B}l7

(e) 6

(D) 210

Q_] 4. Match the items in Group I with the most appropriate separation techniques in Group 2

Group I

? Mixture of glyc i ne and al bumin

Q_ Mixture of 20 and 60 kDa proteins

R. Histones from nuclear extract

S. Lectins

Group!

1. Gas chromatography

2. Dialysis

3. Affinity chromatography

4. S i zc excl u s ion c hrornatography

5. Thin layer chromatography

6. Cat ion exchange chromatography

(A) P-l, Q-4. R·3. S·S (C) P-2. Q-4. R-6. S·3

(B) P&5. Q&3. R'(), S-] (D) P-6, Q.5. R-2. S-4

Q. J 5. In the two half reactions

+ -

Acetaldeh yde + 2 H + 2 e ~ Ethano1

NADH + H& ---+ NAD~ + 2 H+ + 2 e(F = 23.063 cailV)

The tJ. GO [or coupled react j on will be

~ EO =-0,16 V fj, EO = _ 0.32 V

(A) +7.400 cal

(B) -7.400 cal

(C) -22.200 cal

(D) +22.200 cal

Q .16, Match the parameters in G mup I with the correct options in Group 2

!irJ!!!e 1 P- KM Q.~/KM RpKI

S. K,

(A) P~3, Q& r, R-2, 5-4 (C) P-l, Q-2, R-4. S~3

GrouP 2

I. Catalytic efficiency of the enzyme 2, Affinity of enzyme to the in h i hi tor :l- Affinit y of enzyme to the su bstrate 4_ Maximum buffering capacity

(B} P-3. Q-l. R4. S·2 (D) r-r, Q-4. R-2. s.i

Q.l7 _ The rise per residue of a-helix is about 1.5 A. A protein lip<Jns 4 nm bilayer 7 times through its transmembrane Q -hel ical domai n _ Approx i matel y. how many ami no acid resi dues. const i tute the transmembrane domain of I he pl'Ote i n

(A) J05

(B) 450

ee) 30

(D) 190

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Q,18- Match the proteins in Group 1 with their correct functions in Group 2

GrouP I

P. Sh J ke r protein

Q- Bacteriorhodopsin R_ Porin

S. A Be trans.porter

Group 2

1 - Inner me mbrane receptor 2. Act i ve trans port

3- Voltage gated KoIo- channel 4. Light driven H' pump

5 - Membrane f usi on

6_ t3-barrc I 5 i mple diffusion channe I

(B) P-5, Q-3. R-4. S-6 {D} P-3, Q--4, R-6, S·2

(A) P-4. Qa2. R-3. S-5 (C) P-6. Q~J. R-5, S--4

Q.19. The metabolic disorders. Alkaptonuria and Phenylketonuria are caused by defects in the enzymes

P. Glucose- 6-phospbaLas.e

Q. Phenylalanine hydroxylase

R Homogentisate 1,2wdioxygenas.eS, Tyrosinase

(A)Q. R

(B) P. R

(C) P. Q

(D) Q. S

Q.20- Match the metabolic pathways in Group I with the corresponding enzymes in Group 2

Group I P. p-Ox.idation Q- G I ycol ysis

R. G I uconeogenesis

S. Calvin cycle

Groul!.1

1- Ribulose bisphosphate carboxylase 2. Phosphor ructokinase 1

3- Phosphoeno1 pyruvate carboxykinase 4, Thiolase

5- Phosphofructokinase 2

(H) P-3. Q-2. R-4. S-1 (D) P-4. Q-2. R-3. 5-1

(A) P-4. Q·2, R-3. 5-5 (C) P~3. Q-I. R·5. S-2

END OF SECTION - I

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J:BOTANY

Q~l - Q.I0 carry one mark each,

Q,1- When changes in the phenotype Or gene expression occur without changes in the underlying DNA seq lienee. the phe nome non is called

(B) Eugenics

(C) Epigenetics

(D) Epistasis

Q,2. A population growing exponentially can be described by the differential equation dNldl = rN. where dNl til repre sent s the r a te at w hie h the whole popu lut i on grows, N is the size of the population. r is the intrinsic r .... tc of increase. and t is time. According to this equation. the per capita rate of grow rh is

(A) Highest at large N (C) Lowest at large N

(11) COl1SI,:m t

(D) Highest at small N

Q_J, Which one of the following is NOT a plant hormone?

(A) Abscisic acid

(B) B rassi nosteroid

(D) Cytokine

Q,4. Arabidapsis and rice have diploid chromosome numbers of 10 and 24, respectively. Assuming no crossing over laking place. genetic variation among F~ individuals in a genetic cross is likely to he

(A) Same in both species but not ZCrO

(B) More 1 n A rabidopsi s

(C) More in rice

(D) Zero-in both the species

Q-5, Which of the following statements is CORRECT?

(A) Plants adapted to cold environment have higher ratio of "unsaturated (O saturated" fatty acids in their membrane compared to those adapted to hot environment

(B) Plants adapted to cold en vi ron ment ha vc lowe r raiio of "unsaturated 10 saturated" f atty acids j n the i r membra ne compa red 10 1 hose adapted to hot em' i ronrnc nl

(C) Plants Old .. pied to cold environment have same ratio of "unsaturated (0 saturated" fally adds in their membrane compared (0 those adapted to hot environment

(0) Plants de) not have any unsaturated fatty acids in the membrane

Q.6. A sign is hammered into a tree trunk 2 meters above the tree' s base. lf the tree is J 0 meters tall and elongates J meter each year. how high will the sign be after 1O years?

(A) 12 meters

(B) 7 meters

(C) 4 meters

{D) 2 meters

Q.7_ ln the arrangement of flora! p .. rts in a bud. identify the INCORRECT statement

(A) Valvate: where the pcto..tb Or sepals do not overlap but simply touch one another by their

Margins

(B) Sea brous: petals rough and harsh to touch

(C) Epicalyx: an extra calyx found in some flowers outside the c .. Iyx (D) Imbricate: where sep a h. a nd petals overla p cac h other at the mafg i n

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Q.8. The possible genotypes of endosperms borne on a heterozygous (Rr) plant will be

(A) RRR. RRr. Rrr, ITT (C) RR. Rr. rr

(B) RRr, Rrr (0) Rr

Q.9- The amount of chemical energy available to consumers in an ecosystem is best represented by

(A) Gross primary production (C) Respiration

(8) Net primary production (D) Photosynthesis

Q. 10. Free radical scavenging act i vi ty of a medicina II y important pJanl extract can be q uanti fled by

(A) ARTS {2.2· -azino-bis-Gsemyl benzothiozollne-o-sulphonic acid)) method (B) Brad ford method

(C) Wa I kley and Black method (D) K jeldahl met hod

Q.ll - Q.20 carry two marks each.

Q. ~ L Identify the CORREcr statements from the following

P - Lent icel s are the sma Il peres present on the su rface of the S te m OJ branc hes of w ood y plants

Q. GI yox ysomes contain chlorophyll molecu les in their thylakoi d membranes

R. The enzyme ribulose J, 5 bisphosphate carboxylase is. otherwise known as carboxydehydratasc S. ] 8 ATP and 12 NADPH molecules are utilized for fixing 6 molecules of CO~ in the dark

react i on of phocosymbes is

(A) P. Q

(B) P, R

(ClQ. R

(D) P. S

Q.12- Match the following

Group I

P_ Sorghum

Q. Castor

R. Mushroom

S. Cotton

Group II

L Gossypol 2_ S tryc hn i ne 3. Dhurrin

4_ Bungarotoxin 5. Ricin

6- n-Amanitin

Group III

1- Protein

I L G 1 ycosid ic conjugate 111- Alkaloid

rv _ Po] yphenol v, Lipid

v L eye! ic peptide

(A) P-~-iL Q-5~i, R-6-vi. S~] -IV (C) P·2·vi. Q-5-v, R-J- iv, S-6-ii

(B) P-2~iii. Q-4~i"'. R~lwij, S-6--v (D) P·2-i. Q&3-iii. R-4-i\l. S-l-v

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Q-J3-

Idem if y the correc l male h Group I (Anther)

p

Group II (Type or rnation) J Basified

2 Longitudinal 3 Dorsifixcd

4 Adenaic

5 Porous

b Versatile

R

~

s

(A) p.1. Q-4, R-6. S-3 tBl P-2, Q·3. R·5. S· 6 (C) P-l. Q·2, a-s, S·5 (0) P-4. Q-3. R·5. S"()

Q.14. From the, structures gi ven below, identify the compounds

GrooP I (Structure) p

Q

Group I( (Compound) 1 Ethylene

2 Indole but yric acid 3 Nicoline

4 Indole acetic add 5 Gi bbe re Ilk acid 6 Menthol

R

(A) P-6, Q-3, R-4. S-l (B) P-5. Q-2, R-3, SA) (C) P-4, Q-3. R-2. 5-6

(0) P-l, Q-2. R-5, S-{;

Q,15, Regarding (he relationships between two organisms in an ecosystem. match (he following

Group I (Relationship) Group II (Definition)

P. Commensalism 1 Both organisms are benefited

Q, Mutuali~1ll 2 One impeding IhI! success of the other

R. Parasitism 3 One organism benefits but the other is unaffected

S. Arnensal ism 4 One bene fj ted, at her is harmed

(A) p- J • Q·2, R· 3. S-l (B) P-2. Q.3. R-4. S-l

(C) P-3. Q-l, R4. S·2

tD) P-L Q--4. R-3. 5-2

--~,----- ------------~-- -----~--------

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Q _16_ N arne the structures gi ven be low in l he order of thei r appearance and idemi f y corresponding glycosidic linkages

-

1lM~ -0CH,o~ JQ~~

H; Ii H H .. H.Ii ""

i ~:BH Of[B oaHI

~_~ 0 ....__ '--

I ..

II OH H OH K OH

(A) Amylose. C.ellulosc; (a1-4}, (~I -6) (C) S [arc h I Cell ulose; (0.) ~6» (nl----'>4)

(B) Cellulose, Dextran; ((}2-4), (n3-6)

(D) Amyl OPCCl in. Amy lose: (cd -6). (a 1--+4)

Q.17. Identify the CORRECT statements

In A rabidopsis, vernal il.:u ion is associated wit h

P, Chromatin roodification at the FLC (FLOWERING LOCUS C) locus

Q. Degradation of the FLC protein

R. Inact i V31i ng the FLC protei n by post-iranstar ionaJ mod ification S_ Down-regulation of FLC transcript

(A) Q, S

(B) P, S

(C) P. R

(D) Q. R

Q.18. Which of the fnllowing statements in plant respiration are CORRECf?

P. The oxidative Penrose Phosphate Pathway can accomplish the oxidat ion of gl ucose in the S troma of mi lDC hondria

Q, ATP is produced in the reaction step of TeA cycle catalyzed by succinyl CoA synthatase

R _ In addition to Cytoc hrome c ox idase, an alternati ve ox idase enzyme res i sian [ to cyanide reduces oxygen rnclecu I e j n the elec trun I ransport system

S. ln (] I Y01; Y late cycle acet yl C oA react S .... ' ith citrate to fonn a-keto gl utarate

(A) P. R

(B) p. Q

(C) Q, R

(D) Q. S

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Q.19.

Study the following diagram depicting the plant eel I cycle and match the following

(A) P-4.Q~3. R~L S·1 (B) P-2. Q-3. R-l. S-4 (C) p.l.Q-4. R·3. S~2 (0) P-3, Q-J. R-2. S-4

Q.20. In the context of plant development. which of the foJ lowing statements are CORREl..""T?

P_ Cell migration is absent

Q_ Apoptosis plays a majnr role:

R Pattern formation continues throughout life

S. Horneoric changes a re caused by mutations in non-horneodomuin proteins

(A) P. Q> R

(B) Q. R. S

(D) P> R, S

END OF SECTION - J

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K: MICROBIOLOGY

Q.l- Q.I0 carry one mark each,

Q.I, An electron microscope has higher resolution us compared to the light microscope, This is because (A) rbe v, ..... vclength of an electron 1S longer than the wavelength of light

(8) the wavdcngth of an electron is shorter than the wavelength of light

{C) I he cl ect rons can pe net rate t he: sample beuer

(O} they u se d i fferent sta i ns

Q.2. Bacterial (ell lysis by lysozyme is due to the

{A) h yd ro lys i s of ce- 1.4-£ I ycosidic bonds bet ween l he N -acety I g lucosami ne and N -aceryhnuramic

acid

(B) inh i bi li on of ce II wall s ynthesi s (C) h yd rol ysi s of pentapept ide bri dges

(D) hyd rol ys is of B-l.4-gl ycosidic bonds be t Ween {he N -acet y Igl ucosami ne and N -acety I murarni c acid

Q-3- The recombination frequencies between three genes x, y and l are as follows: x-y: 1,{"j(,. y-z: 1.4% and x-z: I _2%_ Then the gene order is

(A) x-z-y

(B) x-y-z

(C) y-x-z

(D) z-x-y

Q,4, A mutant phenotype due to a nonsense mutation can be rescued by a mutation in tRNA gene. This resc u e is <In exa mple of

(A) induced mutation

(B) suppressor mutation

CC} 5 pontancou s mutation

(0) deletion mutation

Q.5- Ames res: is performed (0 detect

(A) mutagen

(8) pH

(C) nutrient st res S

(O) salinity

Q.6, Wild type 1;:, coli forms purple colored colonies on EMB-laclose plate. This is due to t A) increase in pH of the medi urn

(8) decrease in pH of the medium

{C) secretion of purple colored pigment {D) sec rei i on of p- gal ac IO~ i d ase

Q,7. The resistance of a lambda lysogenic Ecoli to re-infection by lambda is mediated by (A) blocking entry of the incoming lambda DNA

(H) degrading (he incoming lambda DNA

(C) blockin]; transcription of the incoming lambda DNA (D) Iriggeri tlg mutation of the lambda receptor of the host

Q.8, Pasteurization of milk is. carried oUL by (A) hoi ling for :;. min

{C) h~al i Il~ ut (d"C for l5 min

( B) heating at 72"C for JO mi n (D) healing al 63uC for 30 min

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Q.9. A growing bacterial culture with II doubling time of 20 min reaches cell density of 2 x 1O~ cells/ ml in 3 hours. How much time would it take to reach (he cell density of 1 x lO\dls /ml?

(A) 200 min

(B) 180 min

(C) ]60 min

(0) 90 min

Q-lO- The quickest way to determine; bacterial growth in terms of viable cells is through

(A} M os l probu ble n u mbcr (M PN) tech nique (C) Pour plate method

(B) Spread plate method (D) Slide c u ltu re technique

Q.ll- Q.20 carry two marks each.

Q-l J. Match the scientist from Group I with the corresponding contribution listed in Group II

Group I Group II

P. Robert Koch

Q. Waller Hesse

R. Louis Paste ur

S. Ferdinand Cohn

I. Oi sco ... ery of endospores

2. Disproved spontaneous generation

3. Discovery of c a ust i ve ugen t of to here ulosi S

4. Use of agar as solid media

5. In vention of microscope

(A) P-S,Q-3.R-4.S·2 (C) P·3,Q-4,R~J .S-5

(B) P·3.Q-4.R-2.S-5 (0) P-3.Q-4,R-2.S-1

Q.l2. Superantigens el icit a. very strong T cell response because they

(A) bind La the specific antigen binding site on the T cell receptors (TCR)

(B} bind to the sire on T cell receptor (TCR) that is. outside the antigen-specific binding site {C} directly acrivate the T cell without the help of antigen presenting cells

(D) direc t I y j nd ucc cytoki ne secret ion by mac rophages

Q.13- MHC-I groove can be loaded with peptides of only 8& to amino acids because

(A) MHC·I groove is closed on both ends

(B) fragments of only 8-10 amino acids are generated in MHC~] bearing cells (C) 62·m.icroglobulin of MHt>1 prevents the binding of large peptides to MHC-l

(0) t3 polypeptides ofMHC·] prevents binding of 8·10 amino acid long peptides to MHC-I

c ~ + +

Q.14. In a lacO iacl/laeO lacZ partial diploid. of the two lacZ enzymes, only the mutant enzyme

- c

(lacZ) is, synthesized constitutively- This observation shows that lact) mutation is

(A) lrans-<iominanl (B) Irans·recessive (C) ds-dornin3nt (0) cis-reces:;;i\'~~

Q.15. Which one of the following events OCCurS in prokaryotes but NOT in eukaryotes?

(A} Protei n phosphorylat ion

{B) RNA polymerase and promoter interactien (C) Control of transcriprion by attenuation

(D) Formation of Okazaki fragments

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Q. l6. Match the pathogen in Gmup I with the corresponding disease in (;roup I(

G roup I Group II

P. Bacteria

Q. Virus

R. Fungi

S- Protozoa

I. Measles.

2 - Candidiasis 3. Malaria

4- Bovine spongiform encephalitis 5- Tuberculosis

(A) P-l, 0.2. R-4. S-5 (C) P-5, Q-l, R-4 . .')·2

(8) P-l, 0-4. R-2. S-3 (0) PAS. Q.1. R-2, S·3

Q.l7. A bacterial culture was diluted 1000 fold and O.l mJ of this diluted sample was spread per plate On nutrient agar. ln a triplicate roo. the number of colonies formed is 121, 93 and 86. The number of colony forming unitslml in the original bacterial culture is

(A) HI

(B) 1<Y

(C) Uy

(0) lcr

Q.l8. Match the microorganism in Group I with the application in Group II

~Q:lUP I Group II

P - A spe rg illus oryza«

Q. Brevibactcrium fiavum

R. Thiobacillus ferroxidans

S. Saccharomyces cerevisiae T- Rhizobium meiitoti

L Metal ore leac h i ng

2. G lucoamy lase prod ucer

3. Bread making

4. Glutamic add producer

5. Penic illin prod ucer

6. Symbiotic nitrogen fixer

(A) PAI.Q-6.R-4.S-5.T-2 (C) P-4,Q-l ,R--6.S·3,T-5

{B) P~2TQ-4.R-l,S·3.T-6 (D) P-6,Q-2.R-3.S-5,T ~ l

Q. J 9. A mutant of E.coli grows normally on glucose or on glycerol but nor on acetate. The most likely metabolic pathway lhul is defective in this mutant is

(A) Glyoxalate cycle

(8) Hexose monophosphaie shunt (C) Krebs cycle

(0) Enmer-Duodoroff pathway

Q.20. Match the resistance mechanism in Group I with the antibiotic in Group II

Group I

Group II

P - f3.- Lac lam ascs

Q - Enhan ccd f 0 I ate metabo1 i srn

R. Drug efflux

S. Phos ph oryl at i on of the drug

T. Mutant RNA polymerase

I. Arninoglycosides

2. Penicillins

3. Sulfa drugs

4. Tetracyclins

5. Naladixic acid

6. Rifamycin

(B) P-3.Q-4.R·l,S-6.T-5 (0) P-l.Q~2,R-3.S-4.T -6

(A) P-2,Q-3,R4.S-5.T-6 (0 P-2,Q-3,R-4.S- J .T -Q

END OJt~ SECTION - K

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L! ZQology

Q.l - Q~10 carry one mark each.

Q.1. From the perspective of developmental origin. which of the following structures is homologous 10 a tortoi se shell ?

(A) Exoskeleton of a lobster (C) Skull of humans

(8) Bones of a fish (D) Feathers of birds

Q .2. Acoelornates arc cha racterized by

(A) roo absence of cavity surrounding the internal organs

(8) the presence of huge body cavity. as in case of terrestrial animals (C) the presence of air sacs. as incase 0 f bi rd s

(D) the absence of brain in a group of extinct species

Q.3. Identify the phylum [hat is characterized by the animals thal have segmented appendages-

(A) Cnidcria (ll) Porifera

(C) Arthropoda (D) Moll usca

QA. Which one of the lollowing is the smallest biological unit capable of evolving over time?

(A) A cell

(C) A population

(B) An i ndi vidual organi sm (D) A species

QS In case of parasites that require multiple hosts to complete their life cycle. what does definitive host mean?

(A) It is the host tbat harbors the sexual stages of the parasite, (B) It is the host in which the parasite reproduces asexually. (C) It is the host in which the parasite feeds.

(O) It is the host in which rhe parasite remains in OJ dormant stage.

Q.6_ Enzymes catalyze biochemical reactions by (A) sequestering the productts)

(B) decreasing the 6G of the react ion (C) increasing the AG of the reaction

(D) stabilizing the transition state of the reaction.

Q _7 _ Wh i ch one of ! be f ollowi Ilg resu lts from Mende I' 5 monohybrid cross is l he SI rongest ev idenc c again s t the blend i ng theory?

(A) 3: 1 ratio or phenotypes in the F 1 generation

(8) All progeny of the Fl generation exhibited the dominant phenotype (C) The recessive phenotype showed up in (he F2 progeny

(0) The observation of incomplete dominance

0-8- In the context of cell differentiation, lateral inhibition is referred 10 as the (A) formation of two sJi:-lin(;l eel I types within a uniform field.

(B) inhibition of formation of a distinct cell type next to an existing cell type. (C) inhibition of stern cells. towards self-renewal.

(D) inhibition of eryihopoesis in the lateral plate mesoderm,

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Q. 9 _ As compared to peptide hormones, steroid hormones lake more lime to act i vate a cellular re sponse because

(A) steroi d hormone s show T1 on-spec i fie bi n d i ng with diverse set s of receptors. (B) steroid hormone acts through a receptor which is a transcripucn factor.

(C) cells that respond to steroid hormones arc dormant in nature,

(D) peptide hormones are not transported through plasma while steroid hormones are.

Q-lO. In allopatric mode of speciation, a new species forms due to (A) Geographic isolation

(8) Genetic drift

(C) Formation of a few fertile individuals that Can nor male with other members of the same species living in the same geographical area

(D) The formation of allopolyploid condition

Q.l1 • Q.20 carry two marks each.

Q, 11, Neurogen (Ngn) a newly discovered protein in chicken. is produced by the notochord and the floor plate (FP). Ngn induces cells of the neural lube (NT) to become neurons. It is known lha~ from ventral to dorsal direction cells ar different le ... els gi v e rise 1.O distinct types of neuronal cells, Which of the following observations will cast a doubt in the claim that Ngn is a morphogen?

(A) N gn is a c ytosolic protein

(B) Artificial mis-expression of Ngn at identical level through out NT does not affect the neuronal cell types formed in the NT

(C} Ngn is an integral membrane protein (D) AU of the above

Q, l2. An alien spec ie s has been discovered wit h very simi lar genet j c rna keup as that of the ex j sting 50 pec ies on planet ell rth with certain di ffe re nee s. The genet ic mate ri al of t his new species is referred to as. DNA"'_ The building blocks of the genetic material is known as Nucleotide*, The proteins (If t he new spec ies (Prete in"') is made up of Ami no Acid s".

II has a I so been d i Soc overed t hat the new s pee ies has 5 d i stinc I N uc leotide '" as opposed to t he four for speci es on planet earth. The new spec ies has 40 different Amino Acids * as opposed to the 20 for species on planet earth. What should be the codon length for this new species (the same for spec ies of planet earth is 3)? It may be a ssumed [hal tbe average codon degeneracy of [he new spec ies is \'ery sirnila r to that of speci es of planet earth,

(A) 2

(B) 3

(C) 4

(D) s

Q. J J. Which one of the following options IS NOT a viable strategy for developing a female c ontracepti ve'? The administration of

(A} a comoi nar ion of s ynthetic progesterone and estrogen (B) synt hetic progesterone alone

(C) ormeloxi fene - a se lecti .. 'e estrogen receptor modulator (0) a synthetic oxytocin

Q, ]4, In the field of community ecology, the term "competitive exclusion" refers to two species that can nOI co-ex i st

(A) in a community i r the n i c hes are identi cal,

(B) in lWO different communities if the niches arc identical. (C) if the ecosystem is imbalanced.

,D} in the event of a volcanic eruption,

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Q. J 5. During immune response, helper T -cell memory against the am igen appears earlier than the B memory cells. Which one of the following is [he primary reason tor this phenomenon?

(A) Affinity of antibody molecules produced by B cells is weaker than those of T cells

(B) B memory c cl L~ prol i ferate at a rate slower than that of T cells

(C) B-cell ac u v at j on req u i res helper T cell s

(0) Thymic selection more rapidly enhances the T cell population than Ji cell population

Q_ J 6- Oceans have enormous. impact on the biosphere. Identify which one of [he following factors is NOT in fluenced by tr.c marine biome.

(A) COl le vel in t he II tmosphere

(B) Climatic change in the terrestrial biome (C) pH of the fresh water bodies

{D} Oxygen level in the biosphere

Q. l7. Certain lung fi she S lhat 1 i ve in small stagnant r resh water pools produce urea as a nitrogenou s waste, What is t he ad vantage of this adaptati on?

(A) Urea form precipitates and does not accumulate in the surrounding water.

(B) Lung fish do not find enough water for production of ammonia and hence the nitrogenous waste is excreted as urea-

(C) The excreted urea rna kes the pool uninh a bha ble to the predators of the lung fi sh. (0) Urea requires much less energy for its synthesis than ammonia.

Q.18. Hamilton's rule measures the probability of whether or not natural selection wouJd favor an altruistic act. Which one of the foHowing statemenrs best explains Hamilton's rule.

N atural select i on wou ld favor an attrui SI ic ac l only when

(A) the receiver and not the altruist is benefited-

(H) the recei ver is <In offspring and NOT a sibling of the altruist.

(C) the benefit to l he recei ve r, reduced by l he coefficient of re latedness, exceeds the cost to the altru i st (let.

(0) the altruist survives in an altruist act to save his/her related individuals.

Q. J 9. In a cross between plants with purple-, and white-colored flowers. the following results were obtained in the F 1 gencrat i 00 (assume that both varier ies are true breed i ng):

100 plants wilh while [lowers; 150 straw yellow: 200 yellow; 245 greenish yellow; :500 green: 440 light blue; 4(X) blue: 300 indigo: 253 purple: and 100 dark purple. These data support which one of the following conclusions?

(A) Flower color in this species does not follow Mendelian inheritance (B) Law of incomplete dominance

(C) Colors are co-dorni nant in th i s species

(0) Flower color in this species is determined by multiple genes

Q.20. Which one of the following is most crucial for [he success of vaccination? (A) Antigen present • nion by T helper cells

{B} Compl erne" I s Y stem

(C) Presen-ce of long-Ii ved antigen-specific lymphocytes (D) Select ion of Bcd b i n the I ymphoi d ti ssue

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