• The resting ECG is often normal in patients with angina.
• Abnormalities include old myocardial infarction, nonspecific ST–T changes, and changes of LVH. • During anginal episodes, as well as during asymptomatic ischemia, the characteristic ECG change is horizontal or downsloping ST-segment depression that reverses after the ischemia disappears .T wave flattening or inversion may also occur. Less frequently, transient ST-segment elevation is observed; this finding suggests severe (transmural) ischemia and often occurs with coronary spasm. A: Tracing taken during an episode of anginal pain that occurred while the patient was at bed rest in the hospital. There is marked ST elevation in leads V 2-5 with ST depression in aVF. B: Tracing taken 30 minutes after A when the patient was pain-free and asymptomatic. The ST segments are isoelectric, and the ECG is normal. Subsequent evaluation, including serial ECGs and enzyme determinations, revealed no evidence of acute myocardial infarction. Although tracing A is quite typical of early infarction, the rapid disappearance of the ST elevation and the absence of clinical and ECG evidence of infarction on subsequent examinations indicate that tracing A represents severe acute but reversible ischemia. Abnormal exercise ECG in a patient with severe three-vessel coronary artery disease and chest pain. The resting ECG shows horizontal ST depression in leads II, aVF, and V 3, and downsloping ST depression in lead V1. After exercise, downsloping ST depression is present in leads II, aVF, and V2-5. The additional 1 or more mm of J point depression as well as the changes in ST-segment configuration constitute an ischemic response, despite the baseline ECG abnormalities.