A prodrug composition is provided which includes a pharmaceutical species and an amino acid having a covalent bond to the pharmaceutical species. Pharmaceutical species is adenosine arabinoside, also known as Ara A and by the trade name vidarabine. Inventive pro drug is transported from the gastrointestinal lumen by a specific transporter and is enzymatically cleaved to yield ara A.
A prodrug composition is provided which includes a pharmaceutical species and an amino acid having a covalent bond to the pharmaceutical species. Pharmaceutical species is adenosine arabinoside, also known as Ara A and by the trade name vidarabine. Inventive pro drug is transported from the gastrointestinal lumen by a specific transporter and is enzymatically cleaved to yield ara A.
A prodrug composition is provided which includes a pharmaceutical species and an amino acid having a covalent bond to the pharmaceutical species. Pharmaceutical species is adenosine arabinoside, also known as Ara A and by the trade name vidarabine. Inventive pro drug is transported from the gastrointestinal lumen by a specific transporter and is enzymatically cleaved to yield ara A.