‫ﺳﺮﻃﺎﻥ ﺭﺍﻫﻲ ﺍﺳﺖ ﻛﻪ ﺑﻪ ﺗﻨﻬﺎﻳﻲ ﻧﺒﺎﻳﺪ ﭘﻴﻤﻮﺩ‬

‫ﮔﺮﻭﻩ ﺍﻳﺮﺍﻧﻲ ﺣﻤﺎﻳﺖ ﺍﺯ ﺑﻴﻤﺎﺭﺍﻥ ﺳﺮﻃﺎﻧﻲ‬

‫ﺁﺷﻨﺎﻳﻲ ﺑﺎ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻭ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ‬

‫ﻣﻘﺪﻣﻪ‬
‫ﭘﻴﻮﻧﺪ ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﻭ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ﻳﻜﻲ ﺍﺯ ﺭﻭﺷﻬﺎﻱ ﺩﺭﻣﺎﻥ‪ ،‬ﻭ ﻣﻌﻤﻮﻻً ﺁﺧﺮﻳﻦ ﺭﺍﻩ ﺩﺭﻣﺎﻥ ﺑﺮﺧﻲ ﺍﺯ ﺳﺮﻃﺎﻧﻬﺎﻱ ﺧﻮﻥ ﻭ ﻟﻨﻒ ﻣﻲﺑﺎﺷﺪ‪ .‬ﻃﻴﻒ‬
‫ﮔﺴﺘﺮﺩﻩﺍﻱ ﺍﺯ ﺑﻴﻤﺎﺭﻳﻬﺎ ﻭ ﻧﺎﻫﻨﺠﺎﺭﻳﻬﺎ ﺷﺎﻣﻞ ﺍﻧﻮﺍﻉ ﺧﺎﺻﻲ ﺍﺯ ﺳﺮﻃﺎﻥ ﻣﺜﻞ ﻟﻮﺳﻤﻲﻫﺎ‪ ،‬ﻟﻨﻔﻮﻣﺎﻫﺎ ﻭ ﻣﻴﻠﻮﻣﺎﻫﺎ‪ ،‬ﺍﺯ ﻃﺮﻳﻖ ﭘﻴﻮﻧﺪ ﺩﺭﻣﺎﻥ ﻣﻲﺷﻮﻧﺪ‪ .‬ﻫﻤﻴﻨﻄﻮﺭ‬
‫ﺑﻴﻤﺎﺭﺍﻧﻲ ﻛﻪ ﺍﺯ ﻧﺎﻫﻨﺠﺎﺭﻳﻬﺎﻱِ ﺍﺭﺛﻲِ ﺳﻴﺴﺘﻢ ﺍﻳﻤﻨﻲ ﻭ ﻣﺘﺎﺑﻮﻟﻴﻜﻲ ﺭﻧﺞ ﻣﻲﺑﺮﻧﺪ ﻧﻴﺰ ﻧﻴﺎﺯﻣﻨﺪ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻫﺴﺘﻨﺪ‪ .‬ﻓﺮﺁﻳﻨﺪ ﭘﻴﻮﻧﺪ‪ ،‬ﭘﻴﭽﻴﺪﻩ ﻭ ﺩﻗﻴﻖ‬
‫ﺍﺳﺖ‪ ،‬ﻭ ﺑﻪ ﺩﻟﻴﻞ ﻣﺤﺪﻭﺩﻳﺘﻬﺎﻱ ﮊﻧﺘﻴﻜﻲ ﻭ ﻓﻴﺰﻳﻮﻟﻮﮊﻳﻜﻲ‪ ،‬ﻳﺎﻓﺘﻦ ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩﺍﻱ ﻛﻪ ﺳﻠﻮﻟﻬﺎﻳﺶ ﺑﺎ ﺑﺪﻥ ﺑﻴﻤﺎﺭ ﺳﺎﺯﮔﺎﺭ ﺑﺎﺷﻨﺪ‪ ،‬ﻛﺎﺭ ﺳﺎﺩﻩﺍﻱ ﻧﻴﺴﺖ‪.‬‬
‫ﺁﺷﻜﺎﺭ ﺍﺳﺖ ﻛﻪ ﻫﺮ ﭼﻪ ﺗﻌﺪﺍﺩ ﺍﻓﺮﺍﺩﻱ ﻛﻪ ﻣﺎﻳﻞ ﺑﻪ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺑﺎﺷﻨﺪ ﺑﻴﺸﺘﺮ ﺑﺎﺷﺪ‪ ،‬ﺑﺨﺖ ﺑﻴﻤﺎﺭ ﺑﺮﺍﻱ ﻳﺎﻓﺘﻦ ﻳﻚ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﺳﺎﺯﮔﺎﺭ ﻭ ﻧﺠﺎﺕ ﺟﺎﻧﺶ ﺍﺯ‬
‫ﺑﻴﻤﺎﺭﻱ ﺑﻴﺸﺘﺮ ﺍﺳﺖ‪ .‬ﻻﺯﻡ ﺑﻪ ﻳﺎﺩﺁﻭﺭﻱ ﺍﺳﺖ ﻛﻪ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺑﺮﺍﻱ ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﻛﺎﻣﻼً ﺑﻲﺧﻄﺮ ﺍﺳﺖ‪.‬‬
‫ﺩﺭ ﺍﺩﺍﻣﺔ ﻣﻄﻠﺐ‪ ،‬ﺷﻤﺎ ﺑﺎ ﺟﺰﻳﻴﺎﺕ ﺑﻴﺸﺘﺮ ﺩﺭﺑﺎﺭﺓ ﻓﺮﺁﻳﻨﺪ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻭ ﺳﺎﺯﻣﺎﻧﻬﺎﻱ ﻣﺘﻮﻟﻲ ﺍﻳﻦ ﻛﺎﺭ ﺩﺭ ﻛﺎﻧﺎﺩﺍ ﺁﺷﻨﺎ ﻣﻲﺷﻮﻳﺪ‪.‬‬

‫ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﻭ ﭘﻴﻮﻧﺪ ﺁﻧﻬﺎ‬

‫ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﻳﺎ ‪ stem cells‬ﻣﻮﺟﻮﺩ ﺩﺭ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ‪ ،‬ﻛﻪ ﮔﺎﻫﻲ ﺳﻠﻮﻟﻬﺎﻱ ﻣﻮﻟﺪ )‪ (progenitor‬ﻳﺎ ﺧﻮﻧﺴﺎﺯ )‪ (hematopoietic‬ﻧﻴﺰ‬
‫ﻧﺎﻣﻴﺪﻩ ﻣﻲﺷﻮﻧﺪ‪ ،‬ﺳﻠﻮﻟﻬﺎﻱ ﻧﺎﺑﺎﻟﻐﻲ ﻫﺴﺘﻨﺪ ﻛﻪ ﻗﺎﺩﺭﻧﺪ ﺗﻤﺎﻡ ﺍﻧﻮﺍﻉ ﺳﻠﻮﻟﻬﺎﻱ ﺧﻮﻧﻲ ﺷﺎﻣﻞ ﮔﻠﺒﻮﻟﻬﺎﻱ ﻗﺮﻣﺰ ﻭ ﺳﻔﻴﺪ ﻭ ﭘﻼﻛﺘﻬﺎ ﻭ ﺍﺟﺰﺍء ﺩﻳﮕﺮ ﺧﻮﻥ ﺭﺍ ﺑﻪ‬
‫ﻭﺟﻮﺩ ﺁﻭﺭﻧﺪ‪ .‬ﺍﻓﺮﺍﺩﻱ ﻛﻪ ﺩﺭ ﺍﺛﺮ ﺑﻴﻤﺎﺭﻱ‪ ،‬ﻗﺪﺭﺕ ﺗﻮﻟﻴﺪ ﺳﻠﻮﻟﻬﺎﻱ ﺧﻮﻧﻲﺷﺎﻥ ﻣﺤﺪﻭﺩ ﻣﻲﺷﻮﺩ‪ ،‬ﻧﻴﺎﺯ ﺩﺍﺭﻧﺪ ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﺳﺎﻟﻤﻲ ﺭﺍ ﺍﺯ ﻳﻚ ﻓﺮﺩ‬
‫ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﺩﺭﻳﺎﻓﺖ ﺩﺍﺭﻧﺪ‪.‬‬
‫ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦِ ﺧﻮﻥ ﺍﺯ ﺩﻭ ﻣﻨﺒﻊ ﺍﺻﻠﻲ ﺑﻪ ﺩﺳﺖ ﻣﻲﺁﻳﻨﺪ‪ -۱ :‬ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ﻳﺎ ﻫﻤﺎﻥ ‪bone marrow‬؛ ‪ -۲‬ﺧﻮﻧﻲ ﻛﻪ ﺩﺭ ﺭﮔﻬﺎ ﺩﺭ ﮔﺮﺩﺵ ﺍﺳﺖ‬
‫ﻭ ﺧﻮﻥ ﻣﺤﻴﻄﻲ )‪ (peripheral blood‬ﻧﺎﻣﻴﺪﻩ ﻣﻲﺷﻮﺩ‪ .‬ﺑﺴﺘﻪ ﺑﻪ ﺍﻳﻦ ﻛﻪ ﻛﺪﺍﻡ ﻳﻚ ﺑﺮﺍﻱ ﺑﻴﻤﺎﺭ ﻣﻨﺎﺳﺐﺗﺮ ﺑﺎﺷﺪ‪ ،‬ﻣﻤﻜﻦ ﺍﺳﺖ ﺍﺯ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ‬
‫ﺩﺭﺧﻮﺍﺳﺖ ﺷﻮﺩ ﻛﻪ ﻳﺎ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ﻳﺎ ﺳﻠﻮﻝ ﺧﻮﻥ ﻣﺤﻴﻄﻲ ﻫﺪﻳﻪ ﻛﻨﺪ‪.‬‬
‫ﺟﻬﺖ ﺁﻣﺎﺩﻩ ﻛﺮﺩﻥ ﺑﻴﻤﺎﺭ ﺑﺮﺍﻱ ﭘﻴﻮﻧﺪ‪ ،‬ﻣﻌﻤﻮﻻً ﺍﻭ ﺭﺍ ﺗﺤﺖ ﺩﻭﺯ ﺯﻳﺎﺩ ﭘﺮﺗﻮﺩﺭﻣﺎﻧﻲ ﻳﺎ ﺷﻴﻤﻲﺩﺭﻣﺎﻧﻲ ﻳﺎ ﻫﺮ ﺩﻭ ﺁﻧﻬﺎ ﻗﺮﺍﺭ ﻣﻲﺩﻫﻨﺪ ﺗﺎ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ﻧﺎﺳﺎﻟﻤﺶ‬
‫ﺍﺯ ﺑﻴﻦ ﺑﺮﻭﺩ‪ .‬ﺑﻴﻤﺎﺭﻱ ﻛﻪ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺩﺭﻳﺎﻓﺖ ﻣﻲﻛﻨﺪ ﺑﺎﻳﺪ ﺗﺎ ﺯﻣﺎﻥ ﺗﺄﻳﻴﺪ ﻣﻮﻓﻘﻴﺖﺁﻣﻴﺰ ﻋﻤﻞ ﭘﻴﻮﻧﺪ ﺩﺭ ﻳﻚ ﺍﻃﺎﻕ ﺍﺳﺘﺮﻳﻞ‪ ،‬ﺟﺪﺍ ﺍﺯ ﺩﻳﮕﺮﺍﻥ‬
‫ﺯﻧﺪﮔﻲ ﻛﻨﺪ‪ .‬ﺩﺭ ﺍﻳﻦ ﻣﺪﺕ‪ ،‬ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ﺟﺪﻳﺪ ﺑﻪ ﺍﻧﺪﺍﺯﺓ ﻛﺎﻓﻲ ﮔﻠﺒﻮﻝ ﺳﻔﻴﺪ ﺗﻮﻟﻴﺪ ﺧﻮﺍﻫﺪ ﻛﺮﺩ ﻛﻪ ﺑﺪﻥ ﺍﻭ ﺭﺍ ﺩﺭ ﺑﺮﺍﺑﺮ ﺑﺎﻛﺘﺮﻳﻬﺎﻱ ﭘﻴﺮﺍﻣﻮﻧﺶ ﻣﺤﺎﻓﻈﺖ‬
‫ﻛﻨﻨﺪ‪.‬‬

‫ﭼﻪ ﻛﺴﻲ ﺑﻪ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻧﻴﺎﺯ ﺩﺍﺭﺩ؟‬

‫ﻫﺮ ﺳﺎﻟﻪ ﺻﺪﻫﺎ ﻛﺎﻧﺎﺩﺍﻳﻲ ﺑﻪ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺍﺣﺘﻴﺎﺝ ﺩﺍﺭﻧﺪ‪ .‬ﺩﺭ ﺍﻛﺘﺒﺮ ﺳﺎﻝ ‪ ،۲۰۰۸‬ﺗﻌﺪﺍﺩ ﺑﻴﻤﺎﺭﺍﻥ ﻣﻨﺘﻈﺮ ﭘﻴﻮﻧﺪ ﺩﺭ ﻛﺎﻧﺎﺩﺍ ‪ ۶۰۰‬ﻧﻔﺮ ﺑﻮﺩ‪ .‬ﺗﻨﻬﺎ ﺩﺭ ﺳﺎﻝ‬
‫‪ ۲۳۳ ،۲۰۰۷‬ﻛﺎﻧﺎﺩﺍﻳﻲ ﻣﻮﻓﻖ ﺑﻪ ﺩﺭﻳﺎﻓﺖ ﭘﻴﻮﻧﺪ ﺷﺪﻧﺪ‪ .‬ﺍﻣﺎ ﺍﻳﻦ ﺍﻣﻜﺎﻥ ﻭﺟﻮﺩ ﺩﺍﺷﺖ ﻛﻪ ﺑﻪ ﺗﻌﺪﺍﺩ ﺑﺴﻴﺎﺭ ﺑﻴﺸﺘﺮﻱ ﻛﻤﻚ ﻛﺮﺩ ﺍﮔﺮ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﺑﻴﺸﺘﺮﻱ ﺩﺭ‬
‫ﺩﺳﺘﺮﺱ ﺑﻮﺩﻧﺪ‪ .‬ﺑﺮﺍﻱ ﺑﺴﻴﺎﺭﻱ ﺍﺯ ﺍﻳﻦ ﺑﻴﻤﺎﺭﺍﻥ‪ ،‬ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻣﻤﻜﻦ ﺍﺳﺖ ﺁﺧﺮﻳﻦ ﻭ ﺑﻬﺘﺮﻳﻦ ﺑﺨﺖ ﺭﻫﺎﻳﻲ ﺍﺯ ﺑﻴﻤﺎﺭﻳﻬﺎﻱ ﺧﻄﺮﻧﺎﻙ ﺑﺎﺷﺪ‪.‬‬

‫‪ www.iraniancancersupport.com‬‬ ‫ﮔﺮﻭﻩ ﺍﻳﺮﺍﻧﻲ ﺣﻤﺎﻳﺖ ﺍﺯ ﺑﻴﻤﺎﺭﺍﻥ ﺳﺮﻃﺎﻧﻲ ‪info@iraniancancersupport.com (۹۰۵) ۲۳۷-۹۰۳۷‬‬

‫ﺩﺭ ﺳﺎﻝ ‪ ۷۷ ،۲۰۰۶‬ﺩﺭﺻﺪ ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦِ ﻣﻮﺭﺩ‪ ‬ﻧﻴﺎﺯِ ﺑﻴﻤﺎﺭﺍﻥِ ﻛﺎﻧﺎﺩﺍﻳﻲ‪ ،‬ﺑﻪ ﺟﺎﻱ ﮔﺮﻓﺘﻪ ﺷﺪﻥ ﺍﺯ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﻛﺎﻧﺎﺩﺍﻳﻲ‪ ،‬ﺍﺯ ﻛﺸﻮﺭﻫﺎﻱ ﺩﻳﮕﺮ ﻭﺍﺭﺩ ﺷﺪﻩ‬
‫ﺑﻮﺩﻧﺪ‪ .‬ﺩﺭ ﺣﺎﻟﻲ ﻛﻪ ﺳﺎﺯﻣﺎﻧﻬﺎﻱ ﻣﺘﻮﻟﻲ ﺍﻳﻦ ﺍﻣﺮ ﺩﺭ ﻛﺎﻧﺎﺩﺍ ﺩﺭ ﺟﺬﺏ ﺍﻓﺮﺍﺩ ﺍﺯ ﻗﻮﻣﻴﺘﻬﺎﻱ ﮔﻮﻧﺎﮔﻮﻥ ﺑﻪ ﺧﻮﺑﻲ ﻋﻤﻞ ﻛﺮﺩﻩ‪ ،‬ﻫﻨﻮﺯ ﻫﻢ ﺟﺎ ﺑﺮﺍﻱ ﺗﻮﺳﻌﻪ ﻭ‬
‫ﮔﺴﺘﺮﺵ ﺍﻳﻦ ﺑﺎﻧﻚ ﺍﻃﻼﻋﺎﺗﻲ ﻭﺟﻮﺩ ﺩﺍﺭﺩ‪ .‬ﺗﺎ ﺍﻛﺘﺒﺮ ‪ ۸۳ ،۲۰۰۸‬ﺩﺭﺻﺪ ﺷﺒﻜﺔ ﻛﺎﻧﺎﺩﺍ ﺭﺍ ﺳﻔﻴﺪﭘﻮﺳﺘﺎﻥ ﺗﺸﻜﻴﻞ ﻣﻲﺩﺍﺩﻧﺪ ﻭ ‪ ۱۷‬ﺩﺭﺻﺪ ﺑﺎﻗﻴﻤﺎﻧﺪﻩ ﺍﺯ ﺳﺎﻳﺮ‬
‫ﮔﺮﻭﻫﻬﺎﻱ ﻗﻮﻣﻲ ﺑﻮﺩﻧﺪ‪ .‬ﺑﻪ ﻋﻼﻭﻩ ﺗﺤﻘﻴﻘﺎﺕ ﻧﺸﺎﻥ ﻣﻲﺩﻫﺪ ﻛﻪ ﻫﺮ ﭼﻪ ﺳﻦ ﺍﻓﺮﺍﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﻛﻤﺘﺮ ﺑﺎﺷﺪ‪ ،‬ﻣﻴﺰﺍﻥ ﻧﺠﺎﺕ ﻃﻮﻻﻧﻲ‪-‬ﻣﺪﺕ ﺑﻴﻤﺎﺭﺍﻥ ﺍﻓﺰﺍﻳﺶ‬
‫ﻣﻲﻳﺎﺑﺪ‪ .‬ﺑﻪ ﻫﻤﻴﻦ ﺩﻟﻴﻞ ﺍﺳﺖ ﻛﻪ ﺍﻳﻦ ﺳﺎﺯﻣﺎﻧﻬﺎ‪ ،‬ﻫﻤﺰﻣﺎﻥ ﺑﺎ ﮔﺴﺘﺮﺵ ﺗﻨﻮﻉ ﻗﻮﻣﻲ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ‪ ،‬ﺗﻼﺵ ﺧﻮﺩ ﺭﺍ ﺑﺮﺍﻱ ﺟﺬﺏ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﺟﻮﺍﻧﺘﺮ‬
‫ﻣﺘﻤﺮﻛﺰ ﻛﺮﺩﻩﺍﻧﺪ ﺗﺎ ﻗﺎﺩﺭ ﺑﻪ ﭘﻮﺷﺶ ﺗﻌﺪﺍﺩ ﺑﻴﺸﺘﺮﻱ ﺍﺯ ﺑﻴﻤﺎﺭﺍﻥ ﺑﺎﺷﻨﺪ‪.‬‬

‫ﭼﮕﻮﻧﻪ ﺳﺎﺯﮔﺎﺭﻱ ﺑﻴﻦ ﺍﻓﺮﺍﺩ ﺗﻌﻴﻴﻦ ﻣﻲﺷﻮﺩ؟‬

‫ﻭﻗﺘﻲ ﻓﺮﺩﻱ ﺑﺮﺍﻱ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺍﻋﻼﻡ ﺁﻣﺎﺩﮔﻲ ﻛﻨﺪ‪ ،‬ﻧﻤﻮﻧﻪﺍﻱ ﺍﺯ ﺩﻱ‪ .‬ﺍ‪‬ﻥ‪ .‬ﺍ‪‬ﻱ )‪ -DNA‬ﻣﺎﺩﺓ ﺳﺎﺯﻧﺪﺓ ﮊﻧﻬﺎﻱ( ﺁﻥ ﻓﺮﺩ ﺍﺯ ﻃﺮﻳﻖ ﻣﺎﻟﻴﺪﻥ ﺳﻮﺍﭖ‬
‫)ﭼﻴﺰﻱ ﺷﺒﻴﻪ ﻳﻚ ﮔﻮﺵ ﭘﺎﻙﻛﻦ( ﺑﻪ ﺩﺍﺧﻞ ﺩﻫﺎﻧﺶ ﮔﺮﻓﺘﻪ ﻣﻲﺷﻮﺩ‪ .‬ﺍﺯ ﺍﻳﻦ ﻣﺎﺩﻩ ﺑﺮﺍﻱ ﺗﻌﻴﻴﻦ ﺗﻌﺪﺍﺩﻱ ﺍﺯ ﺁﻧﺘﻲﮊﻥﻫﺎﻱ ﮔﻠﺒﻮﻟﻬﺎﻱ ﺳﻔﻴﺪ ﺍﻧﺴﺎﻧﻲ‬
‫)‪ (Human Leukocyte Antigen-HLA‬ﺍﺳﺘﻔﺎﺩﻩ ﺷﺪﻩ ﻭ ﺳﭙﺲ ﺑﻪ ﻋﻨﻮﺍﻥ ﺩﺍﺩﻩﻫﺎﻱ ﺍﻃﻼﻋﺎﺗﻲ ﺑﺮﺍﻱ ﺟﺴﺘﺠﻮﻱ ﺑﻴﻤﺎﺭﺍﻥ ﺫﺧﻴﺮﻩ ﻣﻲﮔﺮﺩﺩ‪.‬‬
‫ﺁﻧﺘﻲﮊﻧﻬﺎﻱ ﮔﻠﺒﻮﻟﻬﺎﻱ ﺳﻔﻴﺪ ﺍﻧﺴﺎﻥ ﺷﺎﺧﺼﻬﺎﻱ ﮊﻧﻴﺘﻴﻜﻲﺍﻱ ﻫﺴﺘﻨﺪ ﻛﻪ ﺑﺮ ﺭﻭﻱ ﭘﺮﻭﺗﺌﻴﻦﻫﺎﻱ ﮔﻠﺒﻮﻟﻬﺎﻱ ﺳﻔﻴﺪ ﻗﺮﺍﺭ ﺩﺍﺭﻧﺪ ﻭ ﺑﺮﺧﻲ ﺍﺯ ﺁﻧﻬﺎ ﺑﺮﺍﻱ ﺗﻌﻴﻴﻦ‬
‫ﺳﺎﺯﮔﺎﺭﻱ ﺑﻴﻦ ﺩﻭ ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﻭ ﺩﺭﻳﺎﻓﺖﻛﻨﻨﺪﺓ ﭘﻴﻮﻧﺪ ﺍﻫﻤﻴﺖ ﺩﺍﺭﻧﺪ‪ .‬ﻭﺍﺿﺢ ﺍﺳﺖ ﻛﻪ ﻫﺮ ﭼﻪ ﺩﻭ ﻓﺮﺩ ﺳﺎﺯﮔﺎﺭﺗﺮ ﺑﺎﺷﻨﺪ‪ ،‬ﺑﻴﻤﺎﺭ ﻧﺘﻴﺠﺔ ﺑﻬﺘﺮﻱ ﺍﺯ ﭘﻴﻮﻧﺪ‬
‫ﻣﻲﮔﻴﺮﺩ‪.‬‬
‫ﺩﺭ ﺍﺑﺘﺪﺍ ﻣﺘﺨﺼﺺ ﭘﻴﻮﻧﺪ ﺩﺭ ﺑﻴﻦ ﺍﻓﺮﺍﺩ ﻓﺎﻣﻴﻞ ﺑﻴﻤﺎﺭ ﺑﻪ ﺩﻧﺒﺎﻝ ﻳﻚ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﺳﺎﺯﮔﺎﺭ ﻣﻲﮔﺮﺩﺩ ﻭ ﺩﺭﺧﻮﺍﺳﺖ ﺍﻧﺠﺎﻡ ﺁﺯﻣﺎﻳﺶ ﺑﺮ ﺭﻭﻱ ﺁﻧﻬﺎ ﻣﻲﻛﻨﺪ‪ .‬ﻋﻤﻮﻣﺎً‪،‬‬
‫ﺍﺣﺘﻤﺎﻝ ﺍﻳﻨﻜﻪ ﻳﻜﻲ ﺍﺯ ﺧﻮﺍﻫﺮﻫﺎ ﻳﺎ ﺑﺮﺍﺩﺭﻫﺎ ﺳﺎﺯﮔﺎﺭ ﺑﺎﺷﺪ ﺑﻴﺸﺘﺮ ﺍﺳﺖ‪ .‬ﺍﻣﺎ ﺑﻪ ﻫﺮ ﺣﺎﻝ ﺍﻗﺒﺎﻝ ﻳﺎﻓﺘﻦ ﻳﻚ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﺳﺎﺯﮔﺎﺭ ﺩﺭ ﺑﻴﻦ ﺍﻓﺮﺍﺩ ﻓﺎﻣﻴﻞ ﻛﻤﺘﺮ ﺍﺯ‬
‫‪ %۳۰‬ﺍﺳﺖ ﻭ ﺑﻴﻤﺎﺭﺍﻧﻲ ﻛﻪ ﺍﺯ ﺍﻳﻦ ﺷﺎﻧﺲ ﺑﺮﺧﻮﺭﺩﺍﺭ ﻧﻴﺴﺘﻨﺪ ﺑﺎﻳﺪ ﻣﻨﺘﻈﺮ ﻳﺎﺭﻱ ﺩﺍﻭﻃﻠﺒﻴﻦ ﻏﻴﺮ ﻓﺎﻣﻴﻞ ﺑﻤﺎﻧﻨﺪ‪.‬‬
‫ﻭﻗﺘﻲ ﻣﺘﺨﺼﺺ ﭘﻴﻮﻧﺪ ﺍﻋﻼﻡ ﻛﺮﺩ ﻛﻪ ﻫﻴﭻ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﻣﻨﺎﺳﺒﻲ ﺩﺭ ﻓﺎﻣﻴﻞ ﻭﺟﻮﺩ ﻧﺪﺍﺭﺩ‪ ،‬ﺩﺭﺧﻮﺍﺳﺖ ﺟﺴﺘﺠﻮ ﺑﺮﺍﻱ ﻳﻚ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﻣﻨﺎﺳﺐ ﻏﻴﺮ ﻓﺎﻣﻴﻞ ﺑﻪ‬
‫ﺷﺒﻜﺔ ‪) OneMatch‬ﺑﺨﺸﻲ ﺍﺯ ﺳﺎﺯﻣﺎﻥ ﺍﻧﺘﻘﺎﻝ ﺧﻮﻥ ﻛﺎﻧﺎﺩﺍ( ﺩﺍﺩﻩ ﺧﻮﺍﻫﺪ ﺷﺪ‪ .‬ﺟﺴﺘﺠﻮ ﺩﺭ ﻣﻴﺎﻥ ﺩﺍﻭﻃﻠﺒﻴﻨﻲ ﻛﻪ ﺩﺭ ﻓﻬﺮﺳﺘﻬﺎﻱ ﻣﻠﻲ ﻭ ﺑﻴﻦﺍﻟﻤﻠﻠﻲ ﺛﺒﺖ‬
‫ﻧﺎﻡ ﻛﺮﺩﻩﺍﻧﺪ‪ ،‬ﺍﻧﺠﺎﻡ ﻣﻲﺷﻮﺩ‪ .‬ﺍﻣﺮﻭﺯﻩ‪ ،‬ﺑﻴﻤﺎﺭﺍﻥ ﻛﺎﻧﺎﺩﺍﻳﻲ ﺑﻪ ﻓﻬﺮﺳﺘﻲ ﺍﺯ ‪ ۱۱‬ﻣﻴﻠﻴﻮﻥ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﺩﺳﺘﺮﺳﻲ ﺩﺍﺭﻧﺪ‪ .‬ﺣﺘﻲ ﺩﺭ ﻣﻴﺎﻥ ﺍﻳﻦ ﺗﻌﺪﺍﺩ ﺩﺍﻭﻃﻠﺐ‪ ،‬ﺑﺎ ﺗﻤﺎﻡ‬
‫ﺗﻼﺷﻬﺎﻳﻲ ﻛﻪ ﺻﻮﺭﺕ ﻣﻲﮔﻴﺮﺩ‪ ،‬ﺟﺴﺘﺠﻮ ﻫﻤﻴﺸﻪ ﻣﻮﻓﻘﻴﺖﺁﻣﻴﺰ ﻧﻴﺴﺖ‪.‬‬
‫ﺍﺣﺘﻤﺎﻝ ﭘﻴﺪﺍ ﺷﺪﻥ ﻳﻚ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﺳﺎﺯﮔﺎﺭ ﺩﺭ ﻣﻴﺎﻥ ﺍﻓﺮﺍﺩ ﺟﺎﻣﻌﺔ ﻗﻮﻣﻲ ﻓﺮﺩ ﺑﻴﻤﺎﺭ ﺑﺴﻴﺎﺭ ﺑﻴﺸﺘﺮ ﺍﺳﺖ‪ .‬ﺑﻪ ﻫﻤﻴﻦ ﺩﻟﻴﻞ ﺍﺳﺖ ﻛﻪ ﭘﻴﻮﺳﺘﻦ ﺗﻌﺪﺍﺩ ﺑﻴﺸﺘﺮﻱ ﺍﺯ‬
‫ﻛﺎﻧﺎﺩﺍﻳﻴﻬﺎﻳﻲ ﺍﺯ ﻗﻮﻣﻴﺖﻫﺎﻱ ﻣﺨﺘﻠﻒ ﺑﻪ ﻓﻬﺮﺳﺖ ﺩﺍﻭﻃﻠﺒﺎﻥ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺍﻫﻤﻴﺖ ﭘﻴﺪﺍ ﻣﻲﻛﻨﺪ‪.‬‬

‫ﻣﺮﺍﺣﻞ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﭼﻴﺴﺖ؟‬

‫ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺍﺯ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ‬

‫ﻭﻗﺘﻲ ﻓﺮﺩﻱ ﻣﻲﺧﻮﺍﻫﺪ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻧﺶ ﺭﺍ ﺍﻫﺪﺍء ﻛﻨﺪ‪ ،‬ﺗﺤﺖ ﺑﻲﺣﺴﻲ ﻣﻮﺿﻌﻲ ﻳﺎ ﺑﻴﻬﻮﺷﻲ ﻋﻤﻮﻣﻲ ﻗﺮﺍﺭ ﻣﻲﮔﻴﺮﺩ‪ .‬ﺳﭙﺲ ﺑﺎ ﺳﻮﺯﻥ ﻣﺨﺼﻮﺻﻲ ﻛﻪ ﻭﺍﺭﺩ‬
‫ﺍﺳﺘﺨﻮﺍﻥ ﻟﮕﻦ )‪ (iliac crest‬ﻣﻲﺷﻮﺩ‪ ،‬ﻣﻘﺪﺍﺭﻱ ﺍﺯ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ )ﻛﻪ ﺑﻴﻦ ‪ ۵۰۰‬ﺗﺎ ‪ ۱۵۰۰‬ﺳﻲﺳﻲ ﻣﺘﻐﻴﺮ ﺍﺳﺖ( ﺑﻪ ﺩﺍﺧﻞ ﺳﺮﻧﮓ ﻛﺸﻴﺪﻩ ﻣﻲﺷﻮﺩ‪.‬‬
‫ﺍﻳﻦ ﻋﻤﻞ ﻣﻌﻤﻮﻻً ‪ ۴۵‬ﺗﺎ ‪ ۹۰‬ﺩﻗﻴﻘﻪ ﻃﻮﻝ ﻣﻲﻛﺸﺪ ﻭ ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﻋﻤﻮﻣﺎً ﻫﻤﺎﻥ ﺭﻭﺯ ﺍﺯ ﺑﻴﻤﺎﺭﺳﺘﺎﻥ ﻣﺮﺧﺺ ﻣﻲﺷﻮﺩ‪ .‬ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ‪ ،‬ﺧﻮﺩ ﺭﺍ ﺗﻘﺮﻳﺒﺎً ﺩﺭ‬
‫ﻃﻲ ﺳﻪ ﻫﻔﺘﻪ ﺗﺮﻣﻴﻢ ﻣﻲﻛﻨﺪ‪ .‬ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ﻛﻤﻲ ﺩﺭﺩ ﺩﺭ ﭘﺎﻳﻴﻦ ﻛﻤﺮ ﺧﻮﺩ ﺣﺲ ﺧﻮﺍﻫﻨﺪ ﻛﺮﺩ‪ ،‬ﻛﻪ ﺷﺒﻴﻪ ﺩﺭﺩ ﺯﻣﻴﻦﺧﻮﺭﺩﮔﻲ ﺑﺮ ﺭﻭﻱ ﻳﺦ‬
‫ﺍﺳﺖ‪ .‬ﮔﺰﺍﺭﺷﻬﺎﻳﻲ ﻣﺒﻨﻲ ﺑﺮ ﺧﺴﺘﮕﻲ ﻳﺎ ﻧﺎﺭﺍﺣﺘﻲ ﺩﺭ ﺭﺍﻩ ﺭﻓﺘﻦ ﺑﻪ ﻣﺪﺕ ﭼﻨﺪ ﺭﻭﺯ ﻧﻴﺰ ﻭﺟﻮﺩ ﺩﺍﺭﺩ‪ .‬ﺑﻴﺸﺘﺮ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﭘﺲ ﺍﺯ ﭼﻨﺪ ﺭﻭﺯ ﺑﻪ ﺭﻭﺍﻝ ﻋﺎﺩﻱ‬
‫ﺯﻧﺪﮔﻲ ﺧﻮﺩ ﺑﺎﺯ ﻣﻲﮔﺮﺩﻧﺪ‪ ،‬ﻭﻟﻲ ﺩﺭ ﺑﺮﺧﻲ ﺍﺯ ﺁﻧﻬﺎ ﻣﻤﻜﻦ ﺍﺳﺖ ﺍﻳﻦ ﺯﻣﺎﻥ ﺗﺎ ﭼﻨﺪ ﻫﻔﺘﻪ ﺑﻪ ﻃﻮﻝ ﺑﻴﺎﻧﺠﺎﻣﺪ‪.‬‬

‫‪ www.iraniancancersupport.com‬‬ ‫ﮔﺮﻭﻩ ﺍﻳﺮﺍﻧﻲ ﺣﻤﺎﻳﺖ ﺍﺯ ﺑﻴﻤﺎﺭﺍﻥ ﺳﺮﻃﺎﻧﻲ ‪info@iraniancancersupport.com (۹۰۵) ۲۳۷-۹۰۳۷‬‬

 ‫ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺍﺯ ﺧﻮﻥ ﻣﺤﻴﻄﻲ‬
‫ﻫﻨﮕﺎﻡ ﺟﻤﻊﺁﻭﺭﻱ ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﺍﺯ ﺧﻮﻥ ﻣﺤﻴﻄﻲ‪ ،‬ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﺑﺮﺍﻱ ﻣﺪﺕ ﺣﺪﺍﻗﻞ ‪ ۴‬ﺭﻭﺯ ﻓﺎﻛﺘﻮﺭ ﺗﺤﺮﻳﻚﻛﻨﻨﺪﺓ ﻛُﻠُﻨﻲ ﮔﺮﺍﻧﻮﻟﻮﺳﻴﺖ )‪(G-CSF‬‬
‫ﺭﺍ ﺍﺯ ﻃﺮﻳﻖ ﺗﺰﺭﻳﻖ ﺩﺭﻳﺎﻓﺖ ﻣﻲﻛﻨﺪ‪ .‬ﺍﻳﻦ ﺗﺰﺭﻳﻘﺎﺕ ﺑﺎﻋﺚ ﺍﻓﺰﺍﻳﺶ ﺗﻌﺪﺍﺩ ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﺩﺭ ﺧﻮﻥ ﻣﺤﻴﻄﻲ ﻣﻲﺷﻮﻧﺪ‪ .‬ﺳﭙﺲ ﺑﺮﺍﻱ ﺟﻤﻊﺁﻭﺭﻱ ﺳﻠﻮﻟﻬﺎ‪،‬‬
‫ﺧﻮﻥ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﺍﺯ ﻃﺮﻳﻖ ﺳﻮﺯﻧﻲ ﺑﻪ ﺩﺳﺘﮕﺎﻩ ﺟﺪﺍﻛﻨﻨﺪﺓ ﺧﻮﻥ ﺑﻪ ﻧﺎﻡ ‪ Apheresis‬ﻭﺻﻞ ﻣﻲﮔﺮﺩﺩ‪ .‬ﺧﻮﻥ ﺍﺯ ﻃﺮﻳﻖ ﻟﻮﻟﻪﺍﻱ ﺑﻪ ﺩﺳﺘﮕﺎﻩ ﮔﺮﻳﺰ ﺍﺯ ﻣﺮﻛﺰ‬
‫ﻣﻨﺘﻘﻞ ﺷﺪﻩ‪ ،‬ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﺟﺪﺍ ﮔﺸﺘﻪ ﻭ ﺑﻘﻴﺔ ﺍﺟﺰﺍء ﺧﻮﻥ ﺗﻮﺳﻂ ﺳﻮﺯﻥ ﺩﻳﮕﺮﻱ ﺑﻪ ﺑﺪﻥ ﺑﺮﮔﺮﺩﺍﻧﺪﻩ ﻣﻲﺷﻮﺩ‪ .‬ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺍﺯ ﺧﻮﻥ‬
‫ﻣﺤﻴﻄﻲ ﻋﻮﺍﺭﺽ ﺟﺎﻧﺒﻲ ﻣﺨﺘﻠﻔﻲ ﻣﺜﻞ ﺳﺮﺩﺭﺩ‪ ،‬ﺩﺭﺩ ﻋﻀﻠﻪ ﻳﺎ ﺍﺳﺘﺨﻮﺍﻥ‪ ،‬ﺗﻬﻮﻉ‪ ،‬ﺑﻲﺧﻮﺍﺑﻲ ﻭ ﺧﺴﺘﮕﻲ ﺭﺍ ﮔﺰﺍﺭﺵ ﻛﺮﺩﻩﺍﻧﺪ‪ .‬ﺍﻳﻦ ﻋﻮﺍﺭﺽ ﺩﺭ ﻣﺪﺕ ﻛﻮﺗﺎﻫﻲ‬
‫ﭘﺲ ﺍﺯ ﺍﻫﺪﺍ ﺍﺯ ﺑﻴﻦ ﻣﻲﺭﻭﻧﺪ‪.‬‬

‫ﺷﺒﻜﺔ ‪O ne M atch‬‬
‫”ﺷﺒﻜﺔ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﻭ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ ‪ (One Match Stem Cell and Marrow Network) “OneMatch‬ﺩﺭ ﺍﺑﺘﺪﺍ ﺑﺎ ﻧﺎﻡ ”ﺩﻓﺘﺮ‬
‫ﺛﺒﺖﻧﺎﻡ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﻏﻴﺮﻓﺎﻣﻴﻞ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ“ )‪ (Unrelated Bone Marrow Donor Registry - UBMDR‬ﺩﺭ ﺳﺎﻝ ‪۱۹۸۹‬‬
‫ﺗﺄﺳﻴﺲ ﺷﺪ‪ .‬ﺍﻳﻦ ﺷﺒﻜﻪ ﺗﺤﺖ ﻧﻈﺎﺭﺕ ”ﺳﺎﺯﻣﺎﻥ ﺍﻧﺘﻘﺎﻝ ﺧﻮﻥ ﻛﺎﻧﺎﺩﺍ“ )‪ (Canadian Blood Services‬ﻗﺮﺍﺭ ﺩﺍﺭﺩ ﻭ ﺍﺯ ﻃﺮﻑ ”ﺍﻧﺠﻤﻦ ﺟﻬﺎﻧﻲ‬
‫ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥ“ )‪ (WMDA‬ﺑﻪ ﻋﻨﻮﺍﻥ ﻫﻔﺘﻤﻴﻦ ﻋﻀﻮ ﺍﺯ ‪ ۶۲‬ﻋﻀﻮﻱ ﻛﻪ ﺩﺭ ﺭﺍﺳﺘﺎﻱ ﺍﻳﻦ ﻫﺪﻑ ﻓﻌﺎﻟﻴﺖ ﻣﻲﻛﻨﻨﺪ‪ ،‬ﺑﻪ ﺭﺳﻤﻴﺖ ﺷﻨﺎﺧﺘﻪ‬
‫ﺷﺪﻩ ﺍﺳﺖ‪ .‬ﺷﺒﻜﺔ ‪ OneMatch‬ﺗﻼﺵ ﺧﻮﺩ ﺭﺍ ﻭﻗﻒ ﭘﻴﺪﺍ ﻛﺮﺩﻥ ﻭ ﮔﺮﺩﺁﻭﺭﻱ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻧﻲ ﻛﺮﺩﻩ ﺍﺳﺖ ﻛﻪ ﺳﺎﻟﻢ ﻭ ﻣﺘﻌﻬﺪ ﺑﻪ ﻛﻤﻚ ﻫﺴﺘﻨﺪ ﻭ ﻣﻐﺰ‬
‫ﺍﺳﺘﺨﻮﺍﻧﺸﺎﻥ ﺑﺎ ﺑﻴﻤﺎﺭﺍﻥ ﻧﻴﺎﺯﻣﻨﺪ ﺑﻪ ﭘﻴﻮﻧﺪ ﺩﺭ ﻛﺎﻧﺎﺩﺍ ﻭ ﺳﺮﺍﺳﺮ ﺩﻧﻴﺎ ﺳﺎﺯﮔﺎﺭﻱ ﺩﺍﺭﺩ‪.‬‬

‫ﭘﻴﻮﺳﺘﻦ ﺑﻪ ﺷﺒﻜﺔ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ‪O ne M atch‬‬

‫ﻫﺮ ﻛﺲ ﻛﻪ ﺩﺭ ﺳﻨﻴﻦ ‪ ۱۷‬ﺗﺎ ‪ ۵۰‬ﺳﺎﻟﮕﻲ ﺑﻮﺩﻩ‪ ،‬ﺍﺯ ﺳﻼﻣﺖ ﻋﻤﻮﻣﻲ ﺧﻮﺑﻲ ﺑﺮﺧﻮﺭﺩﺍﺭ ﺑﺎﺷﺪ‪ ،‬ﻣﻲﺗﻮﺍﻧﺪ ﺑﻪ ﺷﺒﻜﻪ ﺑﭙﻴﻮﻧﺪﺩ‪ .‬ﺩﺍﻭﻃﻠﺒﺎﻥ ﻣﺘﻌﻬﺪ ﻫﺴﺘﻨﺪ ﻛﻪ ﺑﻪ ﻫﺮ‬
‫ﺑﻴﻤﺎﺭﻱ ﻛﻪ ﻧﻴﺎﺯﻣﻨﺪ ﭘﻴﻮﻧﺪ ﺍﺳﺖ ﻛﻤﻚ ﻛﻨﻨﺪ‪ .‬ﺩﺭ ﻫﻨﮕﺎﻡ ﺛﺒﺖ ﻧﺎﻡ‪ ،‬ﺷﻤﺎ ﭘﺮﺳﺸﻨﺎﻣﺔ ﻛﻮﺗﺎﻫﻲ ﺭﺍ ﺩﺭ ﻣﻮﺭﺩ ﻭﺿﻊ ﺳﻼﻣﺘﻲﺗﺎﻥ ﭘﺮ ﻣﻲﻛﻨﻴﺪ ﻭ ﻣﻮﺍﻓﻘﺖ‬
‫ﻣﻲﻧﻤﺎﻳﻴﺪ ﻛﻪ ﻧﺎﻣﺘﺎﻥ ﺩﺭ ﻓﻬﺮﺳﺖ ﻗﺮﺍﺭ ﺑﮕﻴﺮﺩ‪ .‬ﻭﻗﺘﻲ ﻛﻪ ﻣﻮﺍﻓﻘﺖﻧﺎﻣﻪ ﻭ ﻓﺮﻡ ﺗﻜﻤﻴﻞ ﺷﺪﺓ ﺛﺒﺖ ﻧﺎﻡ ﺑﻪ ﺩﺳﺖ ﻣﺎ ﺭﺳﻴﺪ‪ ،‬ﺑﺎ ﺷﻤﺎ ﺗﻤﺎﺱ ﻣﻲﮔﻴﺮﻳﻢ ﺗﺎ ﺑﺮﺍﻱ‬
‫ﺍﻧﺠﺎﻡ ﺁﺯﻣﺎﻳﺶ ﻗﺮﺍﺭ ﺑﮕﺬﺍﺭﻳﻢ‪ .‬ﭘﺲ ﺍﺯ ﺍﻳﻦ‪ ،‬ﺍﻃﻼﻋﺎﺕ ﻣﺮﺑﻮﻁ ﺑﻪ ﻧﻮﻉ ‪ HLA‬ﺷﻤﺎ ﻧﻴﺰ ﺩﺭ ﺫﺧﻴﺮﺓ ﺩﺍﺩﻩﻫﺎ ﺛﺒﺖ ﺷﺪﻩ ﻭ ﺩﺭ ﻫﻨﮕﺎﻡ ﺟﺴﺘﺠﻮ ﺑﺮﺍﻱ ﻳﺎﻓﺘﻦ ﻳﻚ‬
‫ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﺑﺎﻟﻘﻮﻩ ﺑﺮﺍﻱ ﻳﻚ ﺑﻴﻤﺎﺭ ﻧﻴﺎﺯﻣﻨﺪ‪ ،‬ﺍﻃﻼﻋﺎﺕ ﺷﻤﺎ ﻫﻢ ﻣﻮﺭﺩ ﺑﺮﺭﺳﻲ ﻗﺮﺍﺭ ﻣﻲﮔﻴﺮﺩ‪.‬‬
‫ﻫﻨﮕﺎﻣﻲ ﻛﻪ ﻳﻚ ﺑﻴﻤﺎﺭ ﻧﻴﺎﺯﻣﻨﺪ ﺑﻪ ﭘﻴﻮﻧﺪ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺍﺳﺖ‪ ،‬ﺷﺒﻜﺔ ‪ OneMatch‬ﺷﺮﻭﻉ ﺑﻪ ﺟﺴﺘﺠﻮﻱ ﺍﻫﺪﺍﻛﻨﻨﺪﻩﺍﻱ ﻣﻲﻛﻨﺪ ﻛﻪ ﺑﺎ ﺑﻴﻤﺎﺭ ﺳﺎﺯﮔﺎﺭ‬
‫ﺑﺎﺷﺪ‪ .‬ﭼﻨﺎﻧﭽﻪ ﻧﺎﻡ ﺷﻤﺎ ﺑﻪ ﻋﻨﻮﺍﻥ ﻳﻚ ﺍﻫﺪﺍﻛﻨﻨﺪﺓ ﺑﺎﻟﻘﻮﻩ ﻇﺎﻫﺮ ﺷﻮﺩ‪ OneMatch ،‬ﺑﺎ ﺷﻤﺎ ﺗﻤﺎﺱ ﻣﻲﮔﻴﺮﺩ‪ .‬ﺍﮔﺮ ﺷﻤﺎ ﺑﺎ ﺍﺩﺍﻣﺔ ﻛﺎﺭ ﻣﻮﺍﻓﻘﺖ ﻛﻨﻴﺪ‪،‬‬
‫ﺁﺯﻣﺎﻳﺶ ﺧﻮﻧﻬﺎﻱ ﺑﻴﺸﺘﺮﻱ ﺍﻧﺠﺎﻡ ﺧﻮﺍﻫﺪ ﺷﺪ ﺗﺎ ﻫﻢ ﺳﺎﺯﮔﺎﺭﻱ ﻛﺎﻣﻞ ﺧﻮﻧﻲ ﺷﻤﺎ ﻣﻮﺭﺩ ﺍﺭﺯﻳﺎﺑﻲ ﻗﺮﺍﺭ ﮔﻴﺮﺩ ﻭ ﻫﻢ ﺍﺯ ﻋﺪﻡ ﻭﺟﻮﺩ ﺑﻴﻤﺎﺭﻳﻬﺎﻱ ﻣﺴﺮﻱ‬
‫ﺍﻃﻤﻴﻨﺎﻥ ﺣﺎﺻﻞ ﺷﻮﺩ‪ .‬ﺳﭙﺲ ﻳﻚ ﭘﺰﺷﻚ ﻣﺘﺨﺼﺺ ﭘﻴﻮﻧﺪ‪ ،‬ﻳﻚ ﻣﻌﺎﻳﻨﺔ ﻛﺎﻣﻞ ﺑﺪﻧﻲ ﺭﺍ ﺩﺭ ﻧﺰﺩﻳﻜﺘﺮﻳﻦ ﻣﺮﻛﺰ ﭘﻴﻮﻧﺪ ﺑﻪ ﺷﻤﺎ )ﻫﻤﺎﻥ ﺑﻴﻤﺎﺭﺳﺘﺎﻧﻲ ﻛﻪ ﻋﻤﻞ‬
‫ﺍﻫﺪﺍء ﺭﺍ ﺩﺭ ﺁﻥ ﺍﻧﺠﺎﻡ ﻣﻲﺩﻫﻴﺪ( ﺑﻪ ﻋﻤﻞ ﻣﻲﺁﻭﺭﺩ‪ .‬ﻭﻗﺘﻲ ﻣﺸﺨﺺ ﺷﺪ ﻛﻪ ﺍﺯ ﻧﻈﺮ ﭘﺰﺷﻜﻲ ﺣﺎﻳﺰ ﺻﻼﺣﻴﺖ ﻫﺴﺘﻴﺪ ﻭ ﺧﻮﺩﺗﺎﻥ ﻧﻴﺰ ﺑﺎ ﺍﺩﺍﻣﺔ ﻛﺎﺭ ﻣﻮﺍﻓﻘﺖ‬
‫ﻛﺮﺩﻳﺪ ﺑﻪ ﺑﻴﻤﺎﺭ ﺍﻃﻼﻉ ﺩﺍﺩﻩ ﺧﻮﺍﻫﺪ ﺷﺪ ﻭ ﺣﺬﻑ ﻣﻐﺰ ﺍﺳﺘﺨﻮﺍﻥِ ﻧﺎﺳﺎﻟﻢِ ﺍﻭ ﺁﻏﺎﺯ ﺧﻮﺍﻫﺪ ﮔﺮﺩﻳﺪ‪.‬‬
‫ﮔﺎﻫﻲ ﺩﺭ ﻃﻲ ﺯﻣﺎﻥ ﺑﻴﻦ ﺛﺒﺖ ﻧﺎﻡ ﺗﺎ ﺍﻫﺪﺍء ﺳﻠﻮﻝ‪ ،‬ﻋﻮﺍﻣﻞ ﺩﻳﮕﺮ ﻣﺜﻞ ﺑﻴﻤﺎﺭﻱ ﭘﺪﻳﺪ ﻣﻲﺁﻳﻨﺪ ﻛﻪ ﺻﻼﺣﻴﺖ ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﺭﺍ ﺑﺮﺍﻱ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺗﺤﺖ‬
‫ﺗﺄﺛﻴﺮ ﻗﺮﺍﺭ ﻣﻲﺩﻫﻨﺪ ﻭ ﺍﻭ ﻣﻤﻜﻦ ﺍﺳﺖ ﻣﺠﺒﻮﺭ ﺷﻮﺩ ﻧﺎﻡ ﺧﻮﺩ ﺭﺍ ﺍﺯ ﻓﻬﺮﺳﺖ ﺣﺬﻑ ﻛﻨﺪ‪.‬‬
‫ﺍﻧﺼﺮﺍﻑ ﺍﺯ ﺛﺒﺖ ﻧﺎﻡ ﺩﺭ ﺷﺒﻜﻪ ﻧﻴﺰ ﺩﺭ ﻫﺮ ﻣﺮﺣﻠﻪﺍﻱ ﺍﻣﻜﺎﻥﭘﺬﻳﺮ ﺍﺳﺖ‪ ،‬ﺍﻣﺎ ‪ OneMatch‬ﺑﺮ ﺭﻭﻱ ﺗﻌﻬﺪ ﺍﻫﺪﺍﻛﻨﻨﺪﮔﺎﻥ ﺍﺯ ﺯﻣﺎﻥ ﺛﺒﺖ ﻧﺎﻡ ﺗﺎ ﻫﻨﮕﺎﻡ ﺍﻫﺪﺍء‬
‫ﺳﻠﻮﻝ ﺣﺴﺎﺏ ﻣﻲﻛﻨﺪ‪ .‬ﺑﻪ ﻭﻳﮋﻩ ﻭﻗﺘﻲ ﻛﻪ ﺑﻴﻤﺎﺭ ﺩﺭ ﺣﺎﻝ ﻃﻲ ﻣﺮﺍﺣﻞ ﺁﻣﺎﺩﻩﺳﺎﺯﻱ ﺍﺳﺖ‪ ،‬ﺍﻧﺼﺮﺍﻑ ﺍﺯ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺧﻄﺮ ﺟﺎﻧﻲ ﺑﺮﺍﻳﺶ ﺩﺭ ﺑﺮ ﺩﺍﺭﺩ‪ .‬ﺩﻟﻴﻠﺶ‬
‫ﺍﻳﻦ ﺍﺳﺖ ﻛﻪ ﺑﻴﻤﺎﺭﺍﻧﻲ )ﻣﺜﻞ ﺑﻴﻤﺎﺭﺍﻥ ﺳﺮﻃﺎﻧﻲ( ﻛﻪ ﺩﺭ ﺍﻧﺘﻈﺎﺭ ﺩﺭﻳﺎﻓﺖ ﺳﻠﻮﻝ ﺑﻨﻴﺎﺩﻳﻦ ﺑﻪ ﺳﺮ ﻣﻲﺑﺮﻧﺪ‪ ،‬ﭘﻴﺶ ﺍﺯ ﭘﻴﻮﻧﺪ ﺗﺤﺖ ﻳﻚ ﺷﻴﻤﻲﺩﺭﻣﺎﻧﻲ ﺑﺴﻴﺎﺭ‬
‫ﻗﻮﻱ ﻫﻤﺮﺍﻩ ﻳﺎ ﺑﺪﻭﻥ ﭘﺮﺗﻮﺩﺭﻣﺎﻧﻲ ﻗﺮﺍﺭ ﻣﻲﮔﻴﺮﻧﺪ ﺗﺎ ﺗﻤﺎﻡ ﺳﻠﻮﻟﻬﺎﻱ ﺳﺮﻃﺎﻧﻲﺷﺎﻥ ﻛﺸﺘﻪ ﺷﻮﺩ‪ .‬ﺍﻣﺎ ﺑﻪ ﺍﻳﻦ ﺗﺮﺗﻴﺐ‪ ،‬ﺳﻠﻮﻟﻬﺎﻱ ﺑﻨﻴﺎﺩﻳﻦ ﺳﺎﻟﻢ ﻭ ﺳﻴﺴﺘﻢ‬
‫ﺍﻳﻤﻨﻲ ﺧﻮﺩ ﺑﻴﻤﺎﺭ ﻧﻴﺰ ﺍﺯ ﺑﻴﻦ ﻣﻲﺭﻭﺩ‪ .‬ﺍﮔﺮ ﻭﻗﺘﻲ ﻛﻪ ﺑﻴﻤﺎﺭ ﺍﻳﻦ ﻣﺮﺣﻠﻪ ﺭﺍ ﻃﻲ ﻛﺮﺩﻩ ﻭ ﺑﺮﺍﻱ ﺩﺭﻳﺎﻓﺖ ﭘﻴﻮﻧﺪ ﺁﻣﺎﺩﻩ ﺍﺳﺖ‪ ،‬ﻧﺎﮔﻬﺎﻥ ﻓﺮﺩ ﺍﻫﺪﺍﻛﻨﻨﺪﻩ ﻧﻈﺮﺵ ﺭﺍ‬
‫ﻋﻮﺽ ﻛﻨﺪ ﻭ ﺍﺯ ﺍﻫﺪﺍء ﺳﻠﻮﻝ ﺍﻣﺘﻨﺎﻉ ﻧﻤﺎﻳﺪ‪ ،‬ﺑﻴﻤﺎﺭ ﻣﻤﻜﻦ ﺍﺳﺖ ﺑﻤﻴﺮﺩ‪.‬‬

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