Osteomyelitis

Modifiable:
\  Poorly nourished
 Obese
 Px with impaired Non-Modifiable:
immune system, chronic Extremes of age
illness or receiving long
term corticosterioid
therapy
 Px with fracture, bruise,
blisters,impetigo and
history of boils

Trauma in bone

Staphylococcus aureus enters

body
Spread of bacteria in location of
trauma

Spreads to medullary ↑WBC, ↑ESR, (+)

cavity to joint INFECTION Blood culture,
Leukocytosis
capsules

Inflammation
Septic arthirits Fever, edema
Neutrophil invasion on affected
site
malaise General Muscle
weakness spasms Production of Formation of subperiostal
purulent exudates abscess (pus)
containing
Vague
bacteria and bone
aching Pus spreads into
fragment tract
thru tissue blood
pain

Extension into Elevated ↑vascularity

metaphysic and periosteum ↑intraosseous
marrow cavity pressure
Stimulation of
osteoblastic
activity Thrombosis of small
↓BP blood vessels

Radiograph: large
irregular cavities and Ischemia with blood
dense areas in necrosis
sequestrum (sequestrum)

New bone is laid over

sequestrum which contains
perforation (involcrum)

Openings in involcrum allow

exudates to escape in
surrounding tissue and skin
by sinus tracts