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Chemotherapy
kills or inhibits the reproduction of neoplastic cells and kills normal cells effects are systemic because it is usually administered systemically Normal cells most profoundly affected include those of the skin, hair, and lining of the gastrointestinal tract, spermatocytes, and hematopoietic cells
Cell cycle phase-specific medications phaseaffect cells only during a certain phase of the reproductive cycle
Combination chemotherapy
the use of several chemotherapy and biotherapy agents in combination to increase the therapeutic response planned to avoid prescribing medications with overlapping toxicities and nadirs (the time during which bone marrow activity and white blood cell counts are at their lowest) or at near the same time to minimize immunosuppresseion may be combined with other treatments, such as surgery and radiation
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