You are on page 1of 1

Long-term Prognosis in Manic-Depressive Illness

A Follow-up Investigation of 111 Patients

Frank O. Shobe, MD; Pacelli Brion, MD,  Arch Gen Psychiatry. 1971;24(4):334-337

In a four-year period 115 manic-depressive patients were seen  and subsequently


followed over a period of 17.8 years. Sixty-five patients had recovered, 24 patients
had improved, and 22 had not fully recovered. Several factors may be related to an
unfavorable course in manic-depressive illness. More women than men did  not
recover. Prognosis was somewhat poorer in those patients  with mania only, or both
manic and depressive attacks of the illness. A history of paranoid delusions seemed
to point to a poor prognosis. The prognosis in manic-depressive illness is relatively
favorable.

You might also like