GENETIC FACTOR AGING PROCESS ENVIRONMENTAL

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STRAIN ON ARTERIAL WALL

LOSS OF ELASTICITY

COLLAGEN AND XALCIFICATION OF ARTERIAL MEDIA

ATHEROSCLEROSIS IN INTIMA NARROWING OF BLOOD VESSEL LUMEN

STIFFNESS OF AORTIC AND PERIPHERAL ARTERIES

CONSTRICTION OF ARTERIOLES

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CARDIOVASCULAR NEUROLOGICAL KENAL

↓ ↓ ↓

TPR, PVR, CC BARORECEPTOR SENSITIVITY SYMPHATIC STIMULATION

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IMPAIRED MYOCARDIAL O2 CHRONIC HYPERTENTIO ANGROTENSIN/ALDOSTERONE

WORKLOAD ON O2 RELEASE

MYOCARDIAL O2 CONSUMPTION
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DYSPENEA ON EXERTION CHANGES IN CSF PRESSURE RENAL BLOOD FLOW

VENTRICULAR HYPERTROPHY DULL HEADACHE IN AN RENAL OXYGEN

CHESTPAIN VERTRIGOTREMORS

↓ ↓ ↓

CARDIAC DECOMPENSATION CEREBRAL EDEMA NOCTURID

CAD SODIUM/WATER RETENTION

↓ ↓ ↓

MYOCARDIAL INFARATION RETINAL HEMORRAGE, BLURRED AZOTEMIA

CARDIAC FAILURE VISION; TIAS EPISTAXIS, RYAIL FAILURE

CEREBRAL ANEURYSM

CEREBRAL HEMORRAGE

CEREBRAL THROMOSIS, CVA