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  • Yawning

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    Ramashanker Yadav
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    Central B-adrenoceptors are involved in regulating yawning responses. Experiments showed that yawning induced by dopamine or cholinergic agonists was increased when combined with beta-adrenoceptor antagonists like propranolol and pindolol. However, the beta-adrenoceptor antagonists alone did not cause yawning. The results suggest that blocking central beta-adrenoceptors facilitates yawning caused by dopamine or acetylcholine, and that the central adrenergic nervous system participates in regulating yawning responses.

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    Central B-adrenoceptors are involved in regulating yawning responses. Experiments showed that yawning induced by dopamine or cholinergic agonists was increased when combined with beta-adrenoceptor antagonists like propranolol and pindolol. However, the beta-adrenoceptor antagonists alone did not cause yawning. The results suggest that blocking central beta-adrenoceptors facilitates yawning caused by dopamine or acetylcholine, and that the central adrenergic nervous system participates in regulating yawning responses.

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    15 views1 page

    Yawning

    Uploaded by

    Ramashanker Yadav
    Central B-adrenoceptors are involved in regulating yawning responses. Experiments showed that yawning induced by dopamine or cholinergic agonists was increased when combined with beta-adrenoceptor antagonists like propranolol and pindolol. However, the beta-adrenoceptor antagonists alone did not cause yawning. The results suggest that blocking central beta-adrenoceptors facilitates yawning caused by dopamine or acetylcholine, and that the central adrenergic nervous system participates in regulating yawning responses.

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    A) Involvement of central B-adrenoceptors in the regulation of YAWNING response

    Yawning was evoked by apomorphine and piribedil, mixed dopamine D1/D2- receptor agonists.
    The apomorphine induced yawning was increased by pindolol, propranolol, indenolol, alprenolol which
    block the central B-adrenoceptors, but not by the peripheral B-adrenoceptor antagonists, carteolol and
    atenolol. These B-adrenoceptor antagonists given alone did not elicit yawning.
    Physostigmine or pilocarpine induced yawning which was enhanced by pindolol and
    propranolol. This enhanced yawning was inhibited by scopolamine.
    Results suggest that the B-adrenoceptor blockade facilitates the occurrence of yawning induced
    by dopaminergic and cholinergic agonists. Therefore , the central adrenergic neuron systems may
    participate in the regulation of yawning responses.

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