rate as the sole source of carbon. The type strain
Citrobacter freundii is biochemically related to Sal-
monella spp., and some strains agglutinate the Sal-
monella polyvalent O antiserum. In addition to
Citrobacter koseri (synonyms, Citrobacter diversus
and Levinea malonatica| and Citrobacter amalo-
naticus (synonym, Levinea amalonatica), five new
species and three unnamed species based on geno-
typic differences have been proposed.*! C, freundii
is a normal inhabitant of the human gastrointesti-
nal tract, but all species of Citrobacter are consid-
ered to be opportunistic human pathogens. The in-
cidence of Citrobacter spp. detected in the
intestinal tract increases with the occurrence of di-
arrhea.”"! Early studies implicated Citrobacter spp.
as a probable cause of diarrhea that could some-
times be traced to food handlers, but the evidence
was not conclusive. Citrobacter spp. are found in
many foods, including meat, freshwater fish, and
spices.!!200.202 Enterotoxigenic C. freundii may cause
diarrhea, and some outbreaks have been food-
borne.” Both C. diversus and C. amalonaticus
cause human infection, but they are not commonly
associated with diarrhea. However, in most coun-
tries, stool specimens are not routinely examined
for Citrobacter spp., and there are no well-devel-
oped systematic procedures for selective isolation of