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    6 views1 page

    GPCRDensensitization

    Uploaded by

    chukhou4you

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    Representation of GPCR desensitization/ resensitization following agonist-activation.

    arr, -arrestin; E, effector enzyme; G, heterotrimeric G protein; GRK, G protein-coupled receptor kinase;
    GRP, G protein-coupled receptor phosphatase; H, hormone; P, phosphate group.
    Taken from G protein-coupled receptor adaptation mechanisms.
    Ferguson and Caron Seminars in Cell & Develop. Biol. 9, 1998: 119 -127

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