(Tentative) Grading

Homework (30%)
Signal Processing for
z
• 2~3 assignments
Brain Waves z Literature presentation (15%)
• 30 minutes per student
z Term project (25%)

Brain Mapping Laboratory

Li-Fen Chen
• 1~2 students for each project
• Presentation
Institute of Brain Science • 10 minutes per project
National Yang-Ming University • Written requirement:
Fall, 2007 • One-page abstract
• Final report

Institute of Brain Science

z Final exam (30%)

Li-Fen Chen Signal Processing for Brain Waves 3

Biomedical Signal Processing Reference Books

National yang-Ming University

z Instructor z Reference books:
• Name: Li-Fen Chen, 陳麗芬 • “An introduction to the event-related potential technique,”
• E-mail: lfchen@ym.edu.tw Steven J. Luck, MIT Press, 2005, ISBN-13: 978-0262621960

• Office: 圖資大樓 840室 • “Biomedical Signal Analysis: A Case-Study Approach,”

Rangaraj M. Rangayyan, Wiley, 2002, ISBN: 0-471-20811-6
• Tel: 28267384
• “Biomedical Signal
g Processingg and Signal
g Modeling,”
g, Eugene
g
• h //b l
http://bml.ym.edu.tw/
d / N. Bruce, Wiley, 2001, ISBN: 0-471-34540-7
z Office hours
• Tue. 10:00am-11:00am
• E-mail reservation
z Little TA
• 李品萱, pshiuan@gmail.com, 6145

Li-Fen Chen Signal Processing for Brain Waves 2 Li-Fen Chen Signal Processing for Brain Waves 4
 Why BWSP?
Sensors and instrumentation to transduce the
phenomenon into an electrical signal
Why BWSP?
z Extract a priori desired information by acquiring
and processing brain signals
z Interpret the nature of a physical process based
on the observation of a signal or on the
observation of how the p process alters the

Brain Mapping Laboratory

characteristics of a signal
Event-Related Magnetic
Field (ERF)
Event-Related Potential
(ERP)

Institute of Brain Science

Li-Fen Chen
Signal analysis to extract information

Example of ERP Experiment

Signal Processing for Brain Waves 5 Li-Fen Chen

Why BWSP?
Signal Processing for Brain Waves 7

National yang-Ming University Figure 1.1 An example of P3 experiment.

The subject views frequent Xs and
infrequent Os presented on a computer
monitor.
z Goal of BWSP
• Basic research for unraveling the mystery of life
• Computer-aided diagnosis (CAD)
• On-line monitoring of patients
• Rehabilitation and sensory aids for the handicapped

Li-Fen Chen Signal Processing for Brain Waves 6 Li-Fen Chen Signal Processing for Brain Waves 8
 Course Goal
z To develop specific skills related to
• Quantifying and compensating
• Effects of measuring devices
• Noise on a signal being measured
• Identifying and separating desired and unwanted

Brain Mapping Laboratory

components of a signal
• Uncovering the nature of phenomena responsible for
generating the signal based on the identification and
interpretation of an appropriate signal model

Institute of Brain Science

Li-Fen Chen

(Tentative) Syllabus
Signal Processing for Brain Waves 9

National yang-Ming University

z 09/12/2007 Introduction to signal processing for brain waves
z 09/19/2007 Neural origins of ERP/ERF
z 09/26/2007 Introduction to ERP/ERF instruments and experiment design
z 10/03/2007 Averaging, artifact rejection, and artifact correction
z 10/10/2007 (vacation)
z 10/17/2007 Time-domain filtering using ICA
z 10/24/2007 Frequency-domain filtering
z 10/31/2007 Impulse response and frequency response
z 11/07/2007 Fourier transform
z 11/14/2007 Wavelet transform and time-frequency analysis
z 11/21/2007 Literature discussion
z 11/28/2007 Plotting, measurement, and analysis
z 12/05/2007 Memory and correlation
z 12/12/2007 Event detection
z 12/19/2007 Coherence analysis
z 12/26/2007 ERP/MEG source localization
z 01/02/2007 Term project presentation
z 01/09/2007 Final Exam

Li-Fen Chen Signal Processing for Brain Waves 10