Conclusion = The very high product molar and mass selectivities, reaching more than 100% (g/g), show that the new process would be a favourable alternative for the industrial production of gluconic acid compared with the discontinuous fungi processes of the last 100 years. = Interesting future research works would include the investigation of continuous gluconic acid production, using biomass retention by cross over filtration, at different residence times and at varying the proportion ratio between filtrate and bleed stream.Continue.. Mathematical models would enable the prediction of experimental results at various stream ratios and facilitate future research designs and experimental plans.