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  • Seizures

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    Oded Gilad
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    This document summarizes different types of seizures, including generalized seizures like tonic-clonic, absence, and infantile spasms, as well as partial seizures. It notes that 10% of the population experiences seizures and 3% experience febrile seizures. Treatment options discussed include carbamazepine, valproic acid, phenobarbital, and phenytoin as generally effective treatments, with valproic acid recommended for myoclonic seizures.

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    This document summarizes different types of seizures, including generalized seizures like tonic-clonic, absence, and infantile spasms, as well as partial seizures. It notes that 10% of the population experiences seizures and 3% experience febrile seizures. Treatment options discussed include carbamazepine, valproic acid, phenobarbital, and phenytoin as generally effective treatments, with valproic acid recommended for myoclonic seizures.

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    15 views1 page

    Seizures

    Uploaded by

    Oded Gilad
    This document summarizes different types of seizures, including generalized seizures like tonic-clonic, absence, and infantile spasms, as well as partial seizures. It notes that 10% of the population experiences seizures and 3% experience febrile seizures. Treatment options discussed include carbamazepine, valproic acid, phenobarbital, and phenytoin as generally effective treatments, with valproic acid recommended for myoclonic seizures.

    Copyright:

    Attribution Non-Commercial (BY-NC)
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    of 1

    SEIZURES

    10% prevalence.
    Febrile seizures- 3% of the population

    Generalized-
    - Tonic / clonic / tonic-clonic
    - Absence
    - Infantile spasms
    o Primary
    o Secondary
     Landau-Kleffner- verbal skills loss, generalized seizures, poor prognosis.
    Tx- everything (anti-epileptic, BZD, steroids, IVIg..)
    - Myoclonic-
    o Benign of infancy- 2y>. No Tx, good prognosis.
    o Of early childgood- 2y<, moderate prognosis
    o Juvenile- 12y<, (the hair combers), Tx with valproic acid for life.
    o Complex- Lennox-Gastaut- accompanying HIE, combined with
    tonic-clonic seizures, poor prognosis.
    o Progressive- associated with mitochondrial / metabolic diseases.

    Partial seizures-
    - Simple- no loss of consciousness (motor, sensory, autonomic..)
    - Complex- with loss of consciousness
    - Partial seizures with generalization
     Rolandic- centro-temporal region, usually falling asleep or waking up.
     Rasmussen encephalitis- ~10y, ongoing partial seizure, associated with
    hemiplegia, poor prognosis

    Treatments-
    - Effective for all- carbamazepine, valproic acid, Phenobarbital, phenytoin
    - Myoclonic- valproic acid
    - Hypsarrythmia- steroids (ACTH), vigabatrin (sabril)
    - Adjuvants- clobazam (frisium), gabapentin (neurontin), topiramate
    (topamax), lamotrigine (lamictal)
     Ethosuximide- for absence (worsening generalized seizures)

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