You are on page 1of 20

Principle of Human

Medical Genetics
Neda M Bogari
Genetics History
Gregor Mendel 1866
R Franklin 1950’s UK

Discover chemical structure of DNA, by


X-ray diffraction images of DNA.
Watson and Crick 1953

US UK
Nobel prize in 1962 made a model of the
DNA molecule
Arthur Kornberg 1956 US

Nobel prize in 1959 for Isolated the 1st


DNA polymerase
F Sanger 1963 UK

Nobel prize in 1958 and 1980. He help


the developed Sequencing procedure for
DNA.
1961-1966

the Genetic code was discovered


the scientists are now able to predict
characteristics by studying DNA. This
leads to genetic engineering, genetic
counseling
Barbara McClintock1983 US

Nobel prize in 1983 for her discovery


that gene are able to change position on
chromosomes
An international team of
scientists Late 1980’s

Start mapping the human genome.


Fingerprinting 1985

The first crime conviction based on DNA


fingerprinting in Portland oregon.
Gene therapy 1990

In US was the 1st gene therapy used on


patients with 4 years boy with severe
combined immunodeficiency for the
first time.
Kary Mullis 1993 US

Nobel prize in 1993 for discovered the


PCR procedure.
Genetic modified food 1994

The first GM food tomatoes have better


flavor and shelf life.
Cloning 1997

Dolly the Sheep the first adult animal


clone
http://web.me.com/bogari/bogari.net/
Welcome.html
1

You might also like