Irritable bowel syndrome

Drug class Bulking agent Generic name Psyllium Methylcellulose Polycarbophil 5-HT4 agonist Osmotic laxative Tegaserod*# Lactulose Milk of magnesia Polyethylene glycol Stimulant laxative Prostone (type-2 chloridechannel activator) Antidiarrheal 5-HT3 antagonist Antibiotic Antispasmodic Cascara sagrada Senna Lubiprostone* Loperamide Alosetron* Rifaximin Hyoscyamine + scopolamine + atropine + Phenobarbital Hyoscyamine sulfate Tricyclic antidepressant Amitriptyline Desipramine Nortriptyline SSRI Fluoxetine Paroxetine Citalopram SNRI Probiotic Duloxetine Bifidobacterium infantis VSL#3 Dose 13 tbsp q.d. 13 tbsp q.d. 24 tablets q.d. 6 mg b.i.d. 12 tbsp q.d.b.i.d. 12 tspn q.d.b.i.d. 17 g in 8 oz fluid 325 mg or 1 tspn qhs 187 mg tablets; 12 tablets qhs 8 g b.i.d. 12 tablets q.d.q.i.d. 0.5 mg to 1 mg q.d.b.i.d. 400 mg t.i.d. 12 tablets t.i.d.q.i.d. 0.125 mg q.i.d. prn, 0.375 mg b.i.d. 10150 mg qhs 10150 mg qhs 10150 mg qhs 1040 mg q.d. 2050 mg q.d. 2040 mg q.d. 30 mg b.i.d. 1 tablet q.d. 1 packet b.i.d. Evidence for IBS