REPLICATIONOFVIRUSES

ds d DNA

ds RNA VIRUS

ss DNA

ss RNA ss

+ss RNA

ds d DNA

ds RNA VIRUS RF

ss DNA

RF

ss

ss RNA ss

+ss RNA

ds d DNA

ds RNA VIRUS

ss DNA

ssRNA ssRNA

+ssRNA

ss RNA ss

+ss RNA

ds d DNA

ds RNA VIRUS ssRNA RNA +ssRNA + RNA ss RNA ss

ss DNA

+ss RNA

ds d DNA

ds RNA
+ss RNA ss RNA

ss DNA VIRUS

mRNA Someinto Some into immaturecore particles ve sense RNA ve senseRNA synthesized

ss RNA ss

+ss RNA

ssDNA (SingleStrandedDNA)Replication
DNAenters bacterium DNAiscoated withssb ConversiontoRFIby y ()strandsynthesis ssb removed

(+)
Nickingand covalent covalent linkageofA geneprotein

Parental phage

(+)
Progeny phage

Particlesassembly usingB,D,F,G,HandJ + products

Unwindingat 5endusingA andrepand and rep and coatingwith ssb;(+)strand synthesis

() ()

ARFIIcomplex