Alkaline Phosphatase Levels: .

Higher-than-normal ALP levels may be due to:

y y y y y y y y y y y y

Anemia Biliary obstruction Bone disease Healing fracture Hepatitis Hyperparathyroidism Leukemia Liver disease Osteoblastic bone cancers Osteomalacia Paget's disease Rickets

Lower-than-normal ALP levels (hypophosphatasemia) may be due to:

y y

Malnutrition Protein deficiency

Additional conditions under which the test may be performed:

y y y y y y y

Alcoholic liver disease (hepatitis/cirrhosis) Alcoholism Biliary stricture Gallstones Giant cell (temporal, cranial) arteritis Multiple endocrine neoplasia (MEN) II Renal cell carcinoma

Heart failure, heart attack, mononucleosis, or kidney cancer can raise ALP levels. A serious infection that has spread through the body (sepsis) can also raise ALP levels. Conditions that lead to malnutrition (such as celiac disease) or are caused by a lack of nutrients in the diet (such as scurvy) can cause low ALP levels.