3.

Ampicillin Sodium Dosage: Adults:The usual adult dosage of ampicillin for the treatment of respiratory tract or skin and skin structure infections is 250500 mg every 6 hours. For the treatment of GI or urinary tract infections, the usual adult dosage is 500 mg every 6 hours. For severe infections, larger doses may be required. The usual adult dosage of ampicillin for the treatment of septicemia or bacterial meningitis is 814 g or 150200 mg/kg daily given parenterally in equally divided doses every 34 hours. For the initial treatment of septicemia or meningitis, ampicillin should be given IV for at least 3 days but may then be given IM. Action Bactericidal action against sensitive organisms; inhibits synthesis of bacterial cell wall, causing cell death. Indication Contraindication Contraindicated with allergies to penicillins, cephalosporins, or other allergens Use cautiously with renal disorder. Adverse reaction Adverse effects reported with ampicillin are similar to those reported with other aminopenicillins; however, diarrhea and rash have been reported more frequently with ampicillin than with other currently available aminopenicillins. Nursing consideration Classification AntibioticPenicillin Nursing consideration Culture infected area before treatment; reculture area if response is not as expected. Check IV site carefully for signs of thrombosis or drug reaction. Do not give IM injections in the same site; atrophy can occur. Monitor injection site. Administer oral drumg on an empty stomach, 1 hr before o 2 hrs after meals with a full glass of water; do not give with fruit juice or soft drinks.