Recent drug discovery patents

1. Multiprotein cancer vaccine 2. Autologous cancer vaccine 3. Cilastatin for decreasing the nephrotoxic effects of drugs without reducing their therapeutic effects 4. siRNA for the treatment of glioblastoma multiforme 5. TOMM40 gene SNP rs10524523 as a drug target for Alzheimer's disease 6. Non-lipidated forms of the HpaA protein as a vaccine target for H. pylori infection 7. DNA vaccines against chikungunya virus 8. Combination therapy using ciglitazone and cisplatin enhances the inhibition of growth of ovarian cancer 9. Novel selective estrogen receptor modulators for the treatment of osteoarthritis 10. Betahistine for treating Eustachian tube dysfunction such as vertigo 11. Lyophilized DNA formulations for the treatment of coronary (CAD) or peripheral artery disease (PAD) 12. siRNA mediated inhibition of thrombospondin-1 (TSP-1) for the treatment of cancer 13. Oligonucleotide decoys for the treatment of pain Stem cells cultured in the presence of HS-2 for the treatment of bone fracture 14. Compounds for differentiation of pluripotent stem cells into insulin producing cells 15. Improved cardiomyogenic differentiation of pluripotent cells with an inhibitor of deltaNp63 expression 16. Antimalarial drug, artemisinin, for the t reatment of herpes viral infections 17. A2A adenosine receptor agonists for treating recurrent tumor metastases following liver resection 18. Leukotriene receptor antagonists for the treatment of snoring and sleep apnea 19. Glucosylceramide synthase inhibitors for the treatment of collapsing glomerulopathy and other glomerular diseases 20. Generation of pancreatic hormone-expressing cells limbal stem cells 21. Method for identifying Plasmodium strains that causes severe malaria