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Classification /Action Anticoagulant Pregnancy risk C Action: Inhibits thrombus and clot production by blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin
Nursing Implications *Contraindicated in presence of allergy to drug, monitor for adverse effects. *Monitor for sign of bleeding or hemorrhage *Monitor lab studies for PT INR, PTT Notify physician per protocol *Monitor lab for Hepatic function test *Monitor pt for adverse reactions to CNS, CV, GI, and skin Monitor lab studies for CBC (Platelet, H&H)
Iv Continuous
IV continuous
T1/2=30-180 min
*antagonist- lepirudin, protamine sulfate(slow IV infusion @ concentration of 1% to equal dose of drug, vitamin K and fresh frozen plasma *metabolized in cells, excreted in urine
S&S OD: Bleeding, nose bleeds, hematuria, tarry stools, easy bruising, petechial formation *Allergies Vancomyin-swelling PCN-Diarrhea Sulfa drugs-Rash Erythromycin-Swelling Augmentin-Diarrhea Sporanox (Itraconazole)-Rash Mycostain-Rash Cardizem (Diltiazem)-Rash Excederine-Rash Iodine-Burns skin Betadine (Providone Iodine)-Blisters Adhesive-Rash Staples-Severe infection
Nursing2011 Drug Handbook with Web Toolkit (Nursing Drug Handbook (LWW)) (Thirty-first Edition ed., pp. 495-499). (2010). Anticoagulants: Heparin Sodium. Philadelphia: Lippincott Williams & Wilkins.