Entamoeba Histolytica Facultative anaerobe- requires complex medium for growth Amoeba- single cell organism Binary fission-

on- replicates in intestinal tract Possess both trophozoite and cyst form Microaerophilic- dwell in lumen or wall of colon Feed on bacteria and tissue cells Multiply rapidly in anaerobic environment Encyst before leaving the gut Cyst are chlorine resistant Amoebic dysentery Dysentery- infection in intestinal tract that causes severe diarrhea with blood and mucus that results in ulceration of intestine and abscess formation Common in tropical and subtropic countries Etiologic agent- entamoeba histolytica Incubation period- 2-4 weeks Period of communicability- during period of entamoeba histolytica cysts are passed which may last for years Reservoir- humans MOT- vehicle borne o o o o H2O that is contaminated with amoebic cyst Fecal- oral route Raw vegetables Oral and anal sex

Susceptible host- all non-immune people Manifestation o o Intermittent diarrhea Stool consist of 1-4 loose to watery, foul smelling, contains blood with mucus

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Flatulence Cramping abdominal pain May lead to liver where abscess is produced

Treatment- metronidazole (DOC) + diloxanide o o o To improve cure rates in intestinal diseases Use to treat infections Per orem or suppositories

Prevention0 hygiene Diagnosis o o o Serological test Alive trophozoite test- direct saline smear method commonly used to check the activities of trophozoite Cyst test