Adverse reactions associated with norepinephrine in dental local anesthesia. P. van der Bijl and A. M.

Victor Department of Oral Medicine and Periodontics, Faculty of Dentistry, University of Stellenbosch, Tygerberg, South Africa. This article has been cited by other articles in PMC. Abstract Two cases are presented in which a 40-yr-old woman and a 20-yr-old woman developed severe headaches after injection of the local anesthetic Xylestesin-F (3% lidocaine with 1:25,000 norepinephrine). It is suggested that these severe headaches may have been associated with acute transient hypertensive episodes following injection of the local anesthetic. A review of the literature indicates that norepinephrine, at least at a concentration of 1:25,000, should be avoided because of its potential for cardiovascular disturbances. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (530K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

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