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PATOPHYSIOLOGY

NON-MODIFIABLE Male 30 yrs old

MODIFIABLE Occupation former sergeant, farmer Diet Lifestyle Diabetes Mellitus, Hyperlipidemia, Hypertension

Hand trauma

Localized ischemia Microvascular contracture Fibroblast proliferation Excessive type III collagen deposition

Contracture of middle finger Nodular thickening of palmar fascia Pain less lump in middle finger, sensitive to touch Cannot grip

DUPUYTRENS CONTRACTURE

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