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Adrenergics and Adrenergic Blockers

I. Adrenergics
A. Function:
Adrenergics
Adrenergic agonists stimulate SNS
sympathomimetics

B. Effects of Adrenergics at receptor sites :

Beta1 receptor Beta2 receptor

Heart Kidney Smooth muscle Lungs Uterus Liver


( gastrointestinal
tract )

Increased Increased
heart renin Activation of
contraction secretion Bronchodilation glycogenolysis

Decreased Relaxation of
Increased Increased
gastrointestinal uterine smooth
heart rate angiotensin
tone and motility muscle

Increased
Increased blood sugar
blood
pressure

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