BI TP CUI K 02 CU 1: Cng thc cu to cc cht: d.

9,10-anthraquinon

(do: e. HOOC-CH=CH-COOH Acid maleic i. Acetonitril k. Qu kh (b i) CU 2: a.

OH

OH CHO

+ CHCl3 + 3KOH
CH3 CH3

+ 3KCl + 2H2O

p-Cresol C ch phn ng:

Cl Cl C Cl
OH
O

K
(+)

OH

:CCl2 + KCl + H20

+ KOH
CH 3
CH3

+ K(+) + H2O

O
(+)

O H

O CHCl2 CCl2

:CCl2

+ 2KOH

- 2KCl. H2O
CH3

CH3

CH3

CH3
OH

O CHO

CHO

+ H2O - OH(-)
CH3

CH3

CU 3: a. (Vit thm phn ng v d: NH4OH CH3-CHO + AgO2 b. B sung thm:

CH3-COOH + Ag

c. B sung thm: Dn xut halogen gn trn carbon bc 3 khi tham gia phn ng th i nhn thng theo c ch n phn t SN1.

d. Danh php D/L c dung cho ng phn quang hc. Chia cc cht quang hot thnh 2 dy: dy D v dy L.

D (+) aldehyde glyceric

L (-) aldehyde glyceric

CU 5: a
H C CH 2

H C Br

CH 2 Br

+ Br2

Styren
H C Br CH 2 Br

(A)
C CH

alcol

+ 2KOH (B)

+ 2KBr + 2H2O

CH C CNa

+ NaNH2 (B)
C CNa

+ NH3

CH 3

+ CH3I (C)
C C CH 3

Pd-BaSO4

H C

C H

CH 3

+ H2 (D)

Cc bi tp dng phn ng chuyn ha, ch c cch l lm i lm li nhiu ln nh cch iu ch/ tnh cht ha hc ca cc cht thi. V nn vit cc phn ng ra nh trn, ch ko nn vit chuyn ha vn tt nh trong bi tr li ca ngi bn. b. Cu ny quan trng, hp cht c kim lc no cng ra. Phi nm vng phn ng ca hp cht c kim.

OH

c.

Cl

to + NaOH
NO2

+ NaCl (A)
OH

NO2
OH

+ Sn/4H+ (A)
O H 3C C O H3 C C O
NO2

+ Sn4+ + 2H2O (B)

NH2

CH3-COOH
HO

HO

NH 2

H N

C O

CH 3

+ CH3-COOH

(C)
O H3C C H N OH

Cl

H2 C

O C Cl
H 3C

O C H N O C O H2 C Cl

+ HCl

(C)

(D)

O H 3C C H N O C O H2 C

C 2H 5
Cl

+ HN
C 2H 5

H3C

H N

C O

H2 C

N(C2H5)2

+ HCl

O H3C C H N O C O H2 C N(C2H5)2

+ HCl

CH3-COOH +

H2N

C O

H2 C

N(C2 H5 )2

(E)