S.Yogesh kanna. I yr M.S. Neuroscience. Department of Anatomy. University of Madras.

Thecorticospinalorpyramidal tractis a collection ofaxonsthat travel between thecerebral cortexof thebrainand thespinal cord. Thismostly contains motoraxons. It actually consists of two separate tracts in the spinal cord: thelateral corticospinal tractand theanterior corticospinal tract. An understanding of these tracts leads to an understanding of why for the most part, one side of the body is controlled by the opposite side of the brain.

Soma upper motor neurons are present in cortex Communicates with lower motor neurons that influence skeletal muscle of various regions Corona radiata Internal capsule Note: here it takes only the ventral route through out

Nerve fibres in the latter part of the medulla cross over To form the motor decussate Fibres which decussate form Lateral corticospinal tract Others form the Anterior corticospinal tract Upper cervical neck, shoulder, eyes, face and pharynx

Lower cervical upper extremity distal part Ventral cortico spinal tract- trunk Lumbar- thigh Sacral -leg and feet

Cerebral palsy(CP) is anumbrella termencompassing a group ofnonprogressive,non-contagiousmotor conditions that cause physical disabilityinhuman development, chiefly in the various areas of body movement. Premature birth unusually stressful birth maternal exposure to drug Interruption of placental circulation oxygen supplies (5-10 min)

The target regions are the cerebral cortex cerebral nuclei, hippocampus and thalamus resulting in abnormalities in motor skills, posture, balance, memory, speech, learning abilities.