)(

. -

.


.
.

(Pshychoactive ) ( Cardiovascular
) (Endocinolgic )
( Respiratory ) . )(Gastrointestinal

.




.

.

). :
) .


:
.
.
.
.

) . )

.
) ( JCAHO
.
.

.

.

.
.
.

) )

)
CHFAfib

Digoxin

Amiodarone

Metoprolol

propranolo
HCL
Labetalol HCL

Acebutolol
Nadolo

HTN - CHF

Captopril

Quinapril

Losartan
potassium

spironolactone

Hydrochlorothiazide

Hydralazine

) (

Felodipine
Nisoldipine

Nicardipine
Nifedipine
Isradipine

Warfarin
sodium

) (

( A

) HMG - CoA
reductase Inhibitors
)(stains

Atorvastatin calcium
Lovastatin
Simvastatin

Lovastatin

( ) (Tyramine





.

)

CNS
medications
MAO inhibitors
Isocarboxazid
phenelzine
sulfate

Tranylcypromine sulfat

) (

Buspirone HCL
Diazepam
Triazolam
Cabamazepine
Nefazodone

Trazodone HCL
Quetiapin
fumarate

Aspirin - ASA
Ketoprofen

 Acetminophen

prpoxyphene
Nabumetene
Flurbiprofen

zolpidem
tartrate

Lithium

Tacrine
HCL

Levodopa Carbidopa

selegiline HCL

)(

Midazolam HCL

) (

Anti
infective agents

Erthromycin base

Erthyromycin steate

Azithromycin

Nitrofurantoin

Isoniazid
Rifampin

)(
Ca )
Mg Fe
) Zn

Teteracycline

Cefuroxime axetil

Cefpodixime proxetil

Amoxicllin

Penicillin V

) (Tyramine



)

Isoniazid
Linezolid

)(

Ca )

Mg Fe
:
) Zn

Floroquinolones
Norfloxacin

Ciprofloxacin
Levofioxacin

Floroquinolons

)(

Itrconazole
Griseofulvin

Ketokonazole

Endocine
medications
Glipizide

Metfornin HCL

Levothyroxine sodium

Bisphosphonates
Alendronte
sodium
Risdronate
sodium
)

) Risdronate
sodium

Tiludronate
disodium

GI tract
medications
sucralfat

Aluminum
Containing antacids

) )

Respiratory tract
medications
SR Theophyllin

Monteiukast sodium

) (

Allergic

conditons

Brompheniramine tannate

Chlorpheniramine maleate

Diphenhydramine

Clemasstine fumarate

Fexofenadine HCL
Cetirine
HCL

)(

) (

Immunosppressants
Cyclosporine
Tacrolimus
Sirolimus

) (

Other
Sildenafil
citrate

) (

Methadone

Loratadine

Mechanisms of food - drug interaction

)
(

 ( K .
(
) (Warfarin
K
) (Thiazides
.

.
Drug absorption
.
) Gastric emptying
) (Gastric PH
.
/
.
.
.
:
Atropine sulphate Diphenoxylate HCI
( A .
ntacids
(proton pump (H2 blockers ) H2 )
) inhitors

) : coated tablets Enteric )
) (Gastric iritation



) (Urinary incontinence )(Congestive heart failue
.

.


) ([Fluoroquinolones
) (Norfloxacin )(Ciprofloxacin

 .

) (
.
.

(Bisphosphonates
) ( Osteoporosis )
( ) (Risedronate (Alendronate)
Tiludronate)

-
.
)(Chelation .
) (
) ( Tetracyclines
) (Floroquinolones


.

.
) (pH
) ( Verapamil .
) (Bioavailities )(Theopylline
.
.
Drug distribution
.


) (Benzodiazepine
.

.
Drug metabolism
.
) (GFJ
p450 enzmes p450 (cytochrome .

(Calcium
A channel anthonist
.
.
( Atkins)
.
) ( Albumin

) (

.
Elemination of drugs
) ( Metabolites

) (Golmerular filtion
(Tubular reabsorption ) .
Biliary excretion
.
Conclusions

.

.

) (primay care physicians