Bioinfomatics 1. The algorithm used for global alignment of sequences is? - Needleman wunsch 2.

Fasta was originally described by - Lipmann and Pearson 3. PERL is an acronym for? - Program extraction and reporting language 4. The acronym UPGMA can be expanded to - Unweighted Pair Group Method with Arithmetic Mean 5. The secondary database, ProDom derives information from which primary database? - SWISSProt and TrEMBL 6. Who proposed shot gun sequencing? - Craig Venter 7. How is the length of the sequence and the E-Value, obtained from BLAST analysis related - Shorter the length higher the E-Value 8. Expand KEGG SSDB - Kyoto encyclopedia of genes and genomes - Sequence Similarity DataBase 9. GENSCAN can predict exon-intron boundaries in genomic sequences True or false - True 10. Name at least 2 NGS technologies : - Lynx Therapeutics' Massively Parallel Signature Sequencing (MPSS),Polony sequencing, 454 pyrosequencing, Illumina (Solexa) sequencing, SOLiD sequencing, Ion semiconductor sequencing, DNA nanoball sequencing, Helioscope(TM) single molecule sequencing, Single Molecule SMRT(TM) sequencing, Single Molecule real time (RNAP) sequencing, Nanopore DNA sequencing, VisiGen Biotechnologies approach 11. The algorithm used for global alignment is - Smith waterman 12. PROSPECT is used for identification of motifs true or false - False 13.