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  • Interesul Moleculei Si Proprietati Farmacologice

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    Daniela Barbu
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    2. Interesul Moleculei Si Proprietati Farmacologice

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    4 views1 page

    Interesul Moleculei Si Proprietati Farmacologice

    Uploaded by

    Daniela Barbu

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    2.Cardiotonic glycoside which presents a buIadienolide-steroid structure.

    Besides ouabain, Irom


    the class oI cardenolides hellebrin is the second unique water soluble cardiotonic glycoside.
    Extremely potent inhibitor oI Na

    /K

    -ATPase (sodium pump) blocking the active eIIlux oI Na


    and reuptake oI K

    oI this membrane enzyme. Shows a positive inotropic eIIect by increasing the


    intracellular Ca
    2
    concentration. Strong immunosuppressor inhibiting T cell activity with much
    higher potency than cortisol or cyclosporin A Induces caspase-dependent apoptosis.

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