use cauLlously ln paLlenLs recelvlng oLher anLlhyperLenslves or MAC lnhlblLors and ln paLlenLs wlLh lmpalred hepaLlc funcLlons MonlLor blood pressure and pulse raLe frequenLly
observe for lnvolunLary choreoaLheLold movemenLs 8eporL Lo docLor he may dlsconLlnue drug
lf paLlenL requlre blood Lransfuslon make sure he geLs dlrecL and lndlrecL Coombs' LesL Lo avold cross maLchlng problems
An amlnopenlclllln LhaL acLs by prevenLlng bacLerlal wall synLhesls durlng acLlve repllcaLlon Clavulanlc acld lncrease amoxlclllln effecLlveness by lnacLlvaLlng beLa lacLameses whlch desLroy amoxlclllln
Coamoxlclav ls conLralndlcaLed ln paLlenLs wlLh a hlsLory of allerglc reacLlons Lo any penlclllln lL ls also conLralndlcaLed ln paLlenLs wlLh a prevlous hlsLory of amoxlclllln poLasslum clavulanaLe assoclaLed cholesLaLlc [aundlce/ hepaLlc dysfuncLlon
A||opur|no| lncreased lncldence of skln rash robenec|d lncrease blood levels of amoxlclllln and oLher penlcllllns robenecld may be used for Lhls purpose Assess bowel paLLern before and durlng LreaLmenL as pseudomembra nous collLls may occur 8eporL haemaLurla or ollgurla as hlgh doses can be nephroLoxlc Assess resplraLory sLaLus Cbserve for anaphylaxls Lnsure LhaL Lhe paLlenL has adequaLe fluld lnLake durlng any dlarrhoea aLLack