Cell L

W @e play a cenLral role ln cellmedlaLed

lmmunlLy
W @ey are called @ cells because Ley maLure ln
Le Lymus
W @ypes
Pelper L
CyLoLoxlc Lc
8egulaLory Ls
naLural klller
% Cu4 @ elper lympocyLes SubseLs
@ produce malnly
CyLoklnes ln Le lnflammaLlon
lln @nl lL3 and lL2
@P2 produce malnly
CyLoklnes LaL sLlmulaLe 8cells
Suppressor cyLoklnes
ll4 lL3 lL6 and lL
ne|per 1 Ce||s
CyLoLoxlc @lympocyLes (C@Ls%
& @ey consLlLuLe 33 @cells
W @ey are acLlvaLed and klll Le vlrus lnfecLed cell or Lumour cell
W @ese cells are also known as Cu8
+
@ cells because Ley express Le
Cu8 proLeln on Lelr surface
W CyLoLoxlc cells become acLlvaLed wen Ley are presenLed wlL
pepLlde anLlgens by MPC class ll
Cytotox|c 1 Ce||s Lyse Infected Ce||s
suppressor 1 ce||s
W re cruclal for Le malnLenance of
lmmunologlcal Lolerance
W @e funcLlon mosL lmporLanL ls Le focus of
lnflammaLlon
W roducen sLop Le lmmune response
W @ls cell lnacLlve anoLer cell L Lo noL produce
necrosls of Le Llssue
-fturf| k|||er
W -fturf| k|||er ce||s are a Lype of cyLoLoxlc
lympocyLe LaL consLlLuLe a ma[or
componenL of Le lmmune sysLem nk cells
play a ma[or role ln Le re[ecLlon of Lumors
and cells lnfecLed by vlruses @ey klll cells by
releaslng small cyLoplasmlc granules of
proLelns called perforln and granzyme LaL
cause Le LargeL cell Lo dle by apopLosls