emulsion gel

..

5003084
5003087
5003123
5003125

..




-
-
-
emulsion gel

1.
(Emulsion) 2

(Emulsifier)

2 (internal or
dispersed phase) (External or
continuous phase)
0.05
25


0.05 : (Transparent)
0.05 0.10 : (Translucent)
0.10 1.00 :
1.00 :

. 2
1.) (Macroemulsion)

0.25 10 ( 1
)

(Coarse
emulsion) (Fine emulsion)
5



2.) (Microemulsion)
( 10 75 )
(Visible light)


O/W W/O

. 3
1.) (W/O Emulsion)
( Cleansing
cream), (Night cream), (Massage cream) (Hormone
cream)
2.) (O/W emulsion)

(Body cream and
lotion), (Vanishing cream), (Sun screen cream), (Foundation
cream)
3.) (Multiple emulsion)
W/O/W O/W/O
W/O/W

O/W
Cold cream O/W/O
. 2
1.) (Lotion) ()
35%
O/W W/O
(Milk or milky lotion)
,
W/O


O/W
(Thickener agent)

2.) ( Cream) ()

 (Waxes) (Fatty acid or fatty alcohol)

(Oils)
O/W
W/O 35 75 %
(Bodying or stiffening agent)
O/W
(Thickener agent) Acacia, Veegum, Methylcellulose
O/W ,
, , , , ,
W/O , ,


3
1. (Water phase)
Acacia, Veegum,
Methylcelluiose, Carbopol Glycerin, propylene glycol glycol

Methylparaben, Sodium benzoate Tween, Sodium lauryl

sulfate Sodium metabisulfite
Cetyl pyridinium chloride, Benzalkonium
chloride


2. (Oil phase) Olive oil, Mineral oil, Castor oil
Stearyl alcohol, Stearic acid, Cetyl alcohol, Lanolin Bee wax, Paraffin wax, Canuba
wax BHT, BHA Span, Emulgin
C 1000

3. (Emulsifier) Tween, Span, Sodium lauryl sulfate
Acacia, Gelatin Bentonite, Colloidal
magnesium aluminium silicate


2

1.

2.

(Surface free energy)

1.
(Heat) (Mechanical agitation)
(Untrasonic vibration) (Electricity)
2.

.


(Monomolecular
film)



(Multimolecular
film)


(Solid
particle
film)

2. emulsion gel
2.1 emulsion gel






(hydrous gel)
-

 quasi-emulsion

suspension gel suspension

hydrogels



emollient
gel base
1.)
1.1 gumexudate
1.2 Biopolymers xanthan gum chitosan
1.3 Cellulose derivatives
1.4 Carbomer resins
1.5 Synthetic polymers
1.6 Montmorillonite clays bentonite
2.)
2.1 Methyl paraben 0.1-0.2% Propyl paraben 0.02-0.05%

2.2 Chelating agent
chelating agent EDTA
cream base
1.)
2.)
3.) Emulsifiers
2
Gel emulsions represent special drug delivery systems. The gel emulsions assurance
interesting and useful possibility as controlled drug delivers systems.

2.2 emulsion gel

i)

hydrophilic polymers

ii)

hydrophobic colloids

iii)

polymerisation

iv)

gel emulsifying agents.

2.3 emulsion gel

- gel base
- gel
2.4 emulsion gel
i)

mucoadhesion

ii)

gastric fluid

iii)

2 emulsion gel.

iv)

form

2.5 emulsion gel

1. Mefenemic emulgel
hydrophobic drugs.
emulgel mefenamic acid, NSAID,
Carbapol 940 . Mentha oil clove oil .

anti-inflammatory analgesic
2 4 diclofenac sodium gel

analgesic anti-inflammatory

emulgel mefenamic acid

anti-inflammatory analgesic
Reference : Rachit Khullar ,, Deepinder Kumar, Nimrata Seth, Seema Saini. Department of Pharmaceutics, Rayat Institute of Pharmacy,
Railmajra, Punjab, India. Received 27 June 2011; Accepted 11 August 2011. Available online 22 August 2011.

http://www.ijppsjournal.com/Vol2Issue1/293.pdf
http://skincare.dermis.net/content/e06technologien/e755/index_eng.html
http://www.maproud.com/article/emulsion.html