The metalation in cyanoacetamide and malononitrile having strongly active methylene group like malondiamide was found to be successful with alkali hydroxide in Liquid Ammonia. Reaction of them with alkyl halide gave alkyl-cyano-acetamide. The speciality of the method is same with that of malondamide synthesis.
The metalation in cyanoacetamide and malononitrile having strongly active methylene group like malondiamide was found to be successful with alkali hydroxide in Liquid Ammonia. Reaction of them with alkyl halide gave alkyl-cyano-acetamide. The speciality of the method is same with that of malondamide synthesis.
The metalation in cyanoacetamide and malononitrile having strongly active methylene group like malondiamide was found to be successful with alkali hydroxide in Liquid Ammonia. Reaction of them with alkyl halide gave alkyl-cyano-acetamide. The speciality of the method is same with that of malondamide synthesis.