u8uCnAML ClasslflcaLlon Mechanlsm of

AcLlon
lnulCA1lCn/CCn18Al
nulCA1lCn
8Cu1LS/
uCSACL
ADvERSE EFFECTS OF
THE DRUC
Slde LffecLs NURS!NC
RESPONS!B!L!T!ES
/PRECAUT!ONS

Cenerlc name
lpraproLlum
SalbuLamol8rand
nameComblvenL

luncLlonalar
asympaLholyLlc
8ronchodllaLor
AnLlchollnerglc
ChemlcalAdre
nerglc beLa2
agonlsL
sympaLhomlm
eLlc
bronchodllaLor

lpraproLlum
bromldeAnLlcholln
erglc chemlcally
relaLed Lo aLroplne
whlch blocks vagally
medlaLed reflexes
by anLagonlzlng Lhe
acLlon of
aceLylchollne
Causes
bronchodllaLlon and
lnhlblLs secreLlon
from serous and
seromucous glands
llnlng Lhe nasal
mucosa
SalbuLamolSLlmulaL
es beLa2 recepLors
of bronchloles Lo
produce
bronchodllaLlon

INDICATIONS
COMBIVENT
Inhalation Aerosol is
indicated Ior use in
patients with chronic
obstructive pulmonary
disease (COPD) on a
regular aerosol
bronchodilator who
continue to have
evidence oI
bronchospasm and
who require a second
bronchodilator.
ConLralndlcaLlon
PypersenslLlvlLy Lo Lhe
drug LachyarryLhmlas
hyperLrophlc
obsLrucLlve
cardlomyopaLhles
hypersenslLlvlLy Lo
aLroplne

uosage1
nebule 23
mg8ouLenebu
llzaLlonlreque
ncyC8P
llne Lremor of skeleLal
muscles palplLaLlons
nervousness urlnary
reLenLlon dyspnea
exacerbaLlon of
sympLoms allerglc
Lype reacLlons
Peadache
dlzzlness dryness of
mouLh LhroaL
lrrlLaLlon nausea
vomlLlng Cl upseL
*Assess cardlo
resplraLory funcLlon
hearL raLe and rhyLhm
resplraLlon raLe and
breaLhlng paLLern and
breaLh soundsnoLe
advenLlLlous sounds
*Lnsure adequaLe
hydraLlon provlde
venLllaLlon Lo prevenL
hyperpyrexla
*uo noL double doses
or lncrease Lhe
frequency of doses
urug should be glven
exacLly as
prescrlbederform
chesL physloLherapy
afLer nebullzaLlon
*8eporL rash eye paln
palplLaLlons Lremors
weakness lrregular
hearLbeaLrovlde
proper nuLrlLlon Clve
small frequenL feedlngs
for Cl
upseL/nausea/vomlLlng