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Oxygen
Blood flow
Hypoxia
Anaerobic metabolism
Phagocytosis
Prostaglandins
Bradykinins
Pus
Vasodilatation
PAIN
Loss of Appetite Compression of nerve ending
Swelling
PATHOPHYSIOLOGY
Hard mass of feces (fecalith) Foreign body in the lumen of appendix Fibrous disease of bowel wall Adhesion/parasitic infestation Calcium phosphate-rich mucus In organic Tumors Viral /bacterial infestation