Drug Study

NAME OF DRUG

CLASSIFICATIO N

MECHANISM OF ACTION

INDICATIONS/ CONTRAINDICATIONS Indi:

SIDE EFFECTS

NURSING RESPONSIBILITIES

Metoclopramid e

Antiemetic Dopaminergi c blocker GI stimulant

Stimulates motility

Relief symptoms of acute and recurrent diabetic gastro paresis. Short term therapy (4-12 weeks) for adults with symptomatic gastro-esophageal reflux who fail to respond to conventional therapy

Restlessnes s Drowsiness Fatigue Insomia Transient hypertensio n Nausea

Asses if the patient has history of allergies to metoclopramide. Monitor BP carefully during IV administration. Monitor extrapyramidal reactions, and consult physician if they occur. Monitor patients with diabetes, arrange for alteration in insulin dose or timing if diabetic control is comprised by alterations in timing of food absorbtion.

of upper GI tract without stimulating gastric, biliary, or pancreatic secretions, appears to sensitize tissues to action of acetylcholine.

Relaxes pyloric

sphincter which when combined with effects on motility, accelerates gastric emptying and intestinal transit.

Contra: Contraindicated with allergy to metaclopramide, Diarrhea

GI hemorrhage, mechanical obstruction or perforation.